Fig. 1. The Bind&Bite reaction. (A) Structure of the parallel, heterodimeric coiled-coil (pdb code 1u0i). (B) Formation of the non-covalent heterodimer. (C) Lack of non-covalent homodimer formation. (D) Activation of Fluo-PepE does not affect the formation of the heterodimer. (E) Covalent heterodimer is stable in GdnHCl. (F) Lack of covalent homodimer formation. See Experimental section for details.
