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. 2023 Jul 31;32(20):2966–2980. doi: 10.1093/hmg/ddad122

Table 5.

Amyotrophic lateral sclerosis disease linked proteins that interact significantly with ORF57

Protein Log-2 fold change  
mCherry-SA vs ORF57-SA
Log-2 fold change  
ORF57 vs ORF57-SA
HNRNPA2B1 3.248* -0.090
VCP 0.877* 0.429*
SQSTM1 0.863* 0.0526
TARDBP 0.721* 4.64*
FUS 2.391* -0.333
TAF15 3.249* 0.446
MATR3 2.04* -0.371

Note. Interactions between ALS-causing genes and ORF57. *FDR-adjusted P-value < 0.05.