Methods |
|
Participants |
Inclusion criteria
Setting/recruitment: NS
Country: Sweden
Children aged under 15 years with at least 2 clinical symptoms of a UTI (including frequency, dysuria, urgency and enuresis) and significant bacteriuria defined as > 105 cfu/mL in a clean catch mid‐stream urine sample
Mean age: 7.2 years
Number: treatment group (19); control group (24)
Sex (M/F): 1/42
Exclusion criteria
Signs or laboratory findings suggesting upper urinary tract involvement (fever > 38.5ºC, flank pain, elevated ESR and leukocytosis); known sensitivity to cephalexin and nitrofurantoin; neurogenic bladder disorder; known structural malformation of the kidneys
|
Interventions |
Treatment group
|
Outcomes |
Persistent bacteriuria (4‐7 days following treatment)
Recurrence (any time during follow‐up; mean 8 months)
Re‐infection (any time during follow‐up; mean 8 months)
|
Notes |
Source of funding: NS |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Unclear risk |
Not reported |
Allocation concealment (selection bias) |
Unclear risk |
Not reported |
Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
Not reported |
Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
All patients randomised were analysed |
Selective reporting (reporting bias) |
Low risk |
Planned outcomes were all analysed |