. Author manuscript; available in PMC: 2023 Oct 4.

Published in final edited form as: Int J Pediatr Otorhinolaryngol. 2021 Apr 18;145:110719. doi: 10.1016/j.ijporl.2021.110719

Table 2:

Trendline and regression analysis of quadratic flow-PEEP relationship in each model

Model	System	Trendline Equation	R²	P-value

Preterm Neonate, Closed Mouth	Optiflow Vapotherm	P_trach = 0.07f² + 0.35f − 0.17 P_trach = 0.68f − 0.10^*	0.98 0.94	<0.001 <0.001^*
Preterm Neonate, Open Mouth	Optiflow Vapotherm	P_trach = 0.03f² + 0.09f - 0.07 P_trach = 0.02f² + 0.19f − 0.10	0.99 0.97	<0.01 <0.001
Term Neonate	Optiflow Vapotherm	P_trach = 0.08f² + 0.18f − 0.08 P_trach = 0.09f² + 0.57f − 0.07	0.99 0.99	<0.001 <0.001
Toddler	Optiflow Vapotherm	P_trach = 0.01f² + 0.04f − 0.04 P_trach = 0.02f² + 0.10f − 0.16	0.99 0.99	<0.001 <0.001
Small Child, Closed Mouth	Optiflow Vapotherm	P_trach = 0.01f² + 0.06f − 0.04 P_trach = 0.02f² + 0.15f − 0.03	0.99 0.99	<0.001 <0.001
Small Child, Open Mouth	Optiflow Vapotherm	P_trach = 0.003f² + 0.02f - 0.02 P_trach = 0.005f² + 0.05f − 0.02	0.99 0.99	<0.001 <0.001

Linear trendline and linear regression analysis p-value for preterm neonate, closed mouth Vapotherm P_trach = Tracheal pressure, cm H₂O; f = Flow, L/min