Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Relationship between mutations in GyrA and ParC and bacteriological response
| Mutation
|
Total no. of strains | Bacteriological response (no. [%] of isolates)
|
||
|---|---|---|---|---|
| GyrA | ParC | Eradicated | Persistent | |
| Wild type | Wild type | 15 | 15 (100) | 0 |
| Ala75Ser | Wild type | 5 | 5 (100) | 0 |
| Ser91Phe | Wild type | 14 | 3 (21.4) | 11 (78.6) |
| Asp95Asn | Wild type | 2 | 2 (100) | 0 |
| Asp95Gly | Wild type | 2 | 2 (100) | 0 |
| Ser91Phe and Asp95Gly | Wild type | 1 | 0 | 1 (100) |
| Ser91Phe and Asp95Gly | Glu91Gly | 1 | 0 | 1 (100) |
| Ser91Phe and Asp95Asn | Ser88Pro | 1 | 0 | 1 (100) |
