Table 5:

Factors Associated with a Shorter Recommended Follow-Up Interval (Years)

	Univariable Analysis			Multivariable Analysis
Factor	Odds Ratio (95% CI)		p-value	Odds Ratio (95% CI)		p-value
Age at encounter (ref: <2 years)			<0.001			<0.001
2–12 years	0.2	(0.1, 0.3)	<0.001	0.3	(0.2, 0.4)	<0.001
≥12 years	0.3	(0.2, 0.5)	<0.001	0.4	(0.3, 0.8)	0.007
Diagnosis era (ref: 1/1/05–12/31/09)	1.9	(1.3, 2.8)	0.002	2.2	(1.5, 3.1)	<0.001
Sex (ref: male)	1.3	(0.8, 2.0)	0.25	1.2	(0.8, 1.8)	0.32
Genetic syndrome (ref: yes)	1.2	(0.6, 2.6)	0.57	0.8	(0.4, 1.6)	0.52
Aortic regurgitation (ref: none)			<0.001			<0.001
Mild	1.8	(1.2, 2.9)	<0.007	1.6	(1.0, 2.5)	0.04
> Mild	7.1	(2.4, 21.1)	<0.001	4.5	(1.4, 14.3)	0.01
Aortic stenosis (ref: none)			<0.001			<0.001
Mild	4.3	(3.0, 6.1)	<0.001	4.1	(2.8, 6.0)	<0.001
> Mild	10.9	(3.6, 33.4)	<0.001	15.6	(4.4, 55.4)	<0.001
Aortic root z-score	1.3	(1.1, 1.5)	<0.001	1.3	(1.1, 1.4)	<0.002
Ascending aorta z-score	1.4	(1.2, 1.5)	<0.001	1.3	(1.1, 1.4)	<0.001