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. 2023 Sep 22;17(9):e0011651. doi: 10.1371/journal.pntd.0011651

Fig 2. Principle of scoring the reliability of cross-reactivity signals.

Fig 2

True cross-reactivity is defined as the combination of a high diagnostic certainty (diagnostic specificity score), a low chance of bias by possible previous arbovirus exposures (arbovirus background score) together with a large study size (study size score). Study data sets considered reliable regarding the serological cross-reactivity signals were selected for analyzing cross-reactivity.