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. 2023 Oct 4;25(Suppl 4):iv1–iv99. doi: 10.1093/neuonc/noad149

Table 10.

One-, Five-, and Ten-Year Relative Survival Ratesa,b (RS) with 95% Confidence Intervals for Brain and Other Central Nervous System Tumors by Histopathology and Behavior, Overall and by NCI Age Group at Diagnosis, CBTRUS Statistical Report: US Cancer Statistics—NPCR and SEER, 2001-2019 (varying)

Histopathology Age Groups (years) All (2004-2019) Malignant (2001-2019)c Non-Malignant (2004-2019)d
N 1-Year RS (95% CI) 5-Year RS (95% CI) 10-Year RS (95% CI) Nf 1-Year RS (95% CI) 5-Year RS (95% CI) 10-Year RS (95% CI) Ne 1-Year RS (95% CI) 5-Year RS (95% CI) 10-Year RS (95% CI)
Diffuse astrocytoma 0-14g 2,080 92.2 (91.0-93.3) 82.4 (80.7-84.1) 80.0 (78.1-81.8) 2,586 91.9 (90.8-92.9) 81.5 (79.9-83.0) 79.4 (77.6-81.0) -- -- -- --
15-39h 6,663 95.7 (95.1-96.1) 78.2 (77.1-79.3) 61.5 (59.9-63.0) 7,919 95.1 (94.6-95.6) 77.1 (76.1-78.1) 59.9 (58.5-61.2) -- -- -- --
40+ 11,841 63.3 (62.4-64.2) 34.0 (33.1-35.0) 25.5 (24.5-26.5) 14,294 61.7 (60.8-62.5) 32.9 (32.0-33.7) 24.2 (23.3-25.1) -- -- -- --
All ages 20,584 76.8 (76.2-77.4) 53.5 (52.7-54.2) 43.0 (42.2-43.9) 24,799 75.6 (75.1-76.2) 52.3 (51.7-53.0) 41.8 (41.1-42.5) 55 86.5 (73.4-93.5) 78.0 (62.7-87.6) 64.9 (46.1-78.5)
Anaplastic astrocytoma 0-14 660 67.5 (63.7-70.9) 25.3 (21.8-28.9) 19.4 (16.0-23.1) 751 66.6 (63.1-69.9) 24.9 (21.6-28.2) 19.6 (16.5-22.9) -- -- -- --
15-39 4,138 92.3 (91.4-93.1) 63.0 (61.3-64.6) 46.8 (44.7-48.8) 4,815 91.4 (90.5-92.1) 61.5 (59.9-63.0) 45.6 (43.8-47.4) -- -- -- --
40+ 10,277 57.5 (56.5-58.5) 20.4 (19.5-21.2) 14.5 (13.6-15.4) 12,169 55.9 (54.9-56.8) 19.8 (19.0-20.6) 14.2 (13.4-15.0) -- -- -- --
All ages 15,075 67.5 (66.7-68.2) 32.2 (31.3-33.0) 23.5 (22.7-24.4) 17,735 65.9 (65.2-66.7) 31.3 (30.5-32.1) 22.9 (22.2-23.7) -- -- -- --
Glioblastoma 0-14 1,119 57.6 (54.6-60.5) 19.5 (17.0-22.0) 16.2 (13.8-18.8) 1,299 57.0 (54.2-59.7) 20.4 (18.1-22.8) 17.2 (15.0-19.6) -- -- -- --
15-39 6,567 76.9 (75.9-78.0) 27.3 (26.1-28.5) 19.0 (17.8-20.2) 7,658 76.1 (75.1-77.0) 27.0 (25.9-28.1) 19.0 (18.0-20.1) -- -- -- --
40+ 119,220 40.9 (40.6-41.2) 5.6 (5.5-5.8) 3.4 (3.2-3.5) 137,363 39.4 (39.1-39.7) 5.3 (5.2-5.5) 3.3 (3.1-3.4) -- -- -- --
All ages 126,906 42.9 (42.6-43.2) 6.9 (6.8-7.1) 4.3 (4.2-4.5) 146,320 41.5 (41.2-41.8) 6.7 (6.5-6.8) 4.3 (4.1-4.4) -- -- -- --
Oligodendroglioma 0-14 269 97.4 (94.6-98.8) 94.3 (90.6-96.5) 92.3 (87.9-95.1) 353 97.2 (94.8-98.5) 94.3 (91.2-96.3) 91.9 (88.2-94.5) -- -- -- --
15-39 3,949 98.6 (98.1-98.9) 92.7 (91.7-93.5) 79.0 (77.3-80.7) 4,823 98.6 (98.2-98.9) 92.4 (91.6-93.2) 78.2 (76.7-79.6) -- -- -- --
40+ 5,526 92.8 (92.1-93.5) 78.2 (76.8-79.4) 64.5 (62.7-66.2) 6,750 92.1 (91.4-92.8) 77.1 (75.9-78.2) 63.0 (61.5-64.5) -- -- -- --
All ages 9,744 95.3 (94.8-95.7) 84.6 (83.7-85.4) 71.4 (70.1-72.6) 11,926 94.9 (94.4-95.3) 83.9 (83.1-84.7) 70.2 (69.1-71.3) -- -- -- --
Anaplastic oligodendroglioma 0-14 -- -- -- -- 51 84.4 (71.1-91.9) 61.5 (46.2-73.6) 50.9 (35.3-64.6) -- -- -- --
15-39 -- -- -- -- 1,575 95.6 (94.4-96.5) 78.5 (76.1-80.6) 64.1 (61.1-67.0) -- -- -- --
40+ 3,032 86.2 (84.9-87.4) 61.0 (59.0-63.0) 48.1 (45.6-50.5) 3,713 84.4 (83.2-85.6) 57.2 (55.4-59.0) 44.7 (42.6-46.7) -- -- -- --
All ages 4,342 89.1 (88.0-90.0) 66.8 (65.2-68.4) 53.0 (51.0-55.0) 5,339 87.7 (86.8-88.6) 63.6 (62.2-65.1) 50.6 (48.9-52.3) -- -- -- --
Oligoastrocytic tumors 0-14 147 91.2 (85.2-94.8) 78.5 (70.8-84.4) 76.1 (68.0-82.3) 187 90.4 (85.1-93.9) 76.2 (69.3-81.7) 74.3 (67.3-80.1) -- -- -- --
15-39 2,400 97.5 (96.8-98.1) 81.2 (79.5-82.7) 61.0 (58.7-63.2) 2,933 97.3 (96.6-97.8) 79.9 (78.3-81.3) 59.7 (57.7-61.7) -- -- -- --
40+ 2,896 82.7 (81.2-84.0) 54.7 (52.8-56.6) 43.7 (41.7-45.8) 3,497 81.7 (80.4-83.0) 53.2 (51.4-54.9) 42.1 (40.2-43.9) -- -- -- --
All ages 5,443 89.5 (88.6-90.3) 67.1 (65.8-68.4) 52.3 (50.8-53.8) 6,617 88.9 (88.1-89.6) 65.7 (64.5-66.9) 50.9 (49.5-52.2) -- -- -- --
Pilocytic astrocytoma 0-14 8,289 99.0 (98.7-99.2) 97.3 (96.9-97.7) 95.9 (95.3-96.4) 9,383 98.8 (98.6-99.0) 97.1 (96.7-97.4) 95.5 (95.0-96.0) 232 100.0 (**-**) -- --
15-39 3,977 98.5 (98.1-98.9) 94.7 (93.9-95.4) 93.0 (91.9-94.0) 4,608 98.4 (98.0-98.8) 94.6 (93.8-95.3) 92.9 (91.9-93.7) -- -- -- --
40+ 1,351 91.9 (90.2-93.3) 79.6 (76.9-82.1) 77.2 (73.6-80.3) 1,547 91.5 (89.9-92.9) 79.0 (76.4-81.3) 77.1 (73.9-79.9) -- -- -- --
All ages 13,617 98.1 (97.9-98.4) 94.8 (94.4-95.2) 93.2 (92.6-93.7) 15,538 98.0 (97.7-98.2) 94.6 (94.1-94.9) 92.9 (92.4-93.4) 267 100.0 (**-**) -- --
Unique astrocytoma variants 0-14 1,036 97.7 (96.5-98.4) 94.8 (93.1-96.1) 92.4 (90.1-94.2) 383 95.7 (93.1-97.4) 87.8 (83.8-90.9) 82.6 (77.5-86.7) 698 98.6 (97.3-99.3) 98.0 (96.4-98.8) 96.6 (94.3-98.0)
15-39 968 96.8 (95.4-97.7) 86.8 (84.2-89.0) 82.0 (78.8-84.8) 719 96.6 (95.0-97.8) 82.5 (79.2-85.3) 77.7 (73.8-81.1) 342 97.0 (94.5-98.4) 94.2 (90.7-96.4) 91.0 (86.2-94.2)
40+ 349 84.0 (79.5-87.6) 59.3 (53.1-64.8) 51.1 (43.9-57.8) 300 81.6 (76.5-85.7) 52.8 (46.4-58.9) 48.0 (40.7-54.8) 83 91.5 (82.1-96.1) 82.6 (69.7-90.4) 64.6 (46.4-77.9)
All ages 2,353 95.3 (94.3-96.1) 86.4 (84.7-87.8) 82.2 (80.2-84.0) 1,402 93.2 (91.7-94.4) 77.7 (75.2-79.9) 72.8 (69.9-75.5) 1,123 97.6 (96.5-98.4) 95.8 (94.2-96.9) 92.8 (90.5-94.6)
Ependymal tumors 0-14 2,467 95.6 (94.7-96.4) 80.3 (78.5-82.0) 72.0 (69.7-74.1) 2,577 94.7 (93.7-95.5) 76.8 (75.0-78.5) 67.3 (65.1-69.4) 281 99.7 (97.0-100.0) 97.6 (94.3-99.0) 97.6 (94.3-99.0)
15-39 5,029 98.4 (97.9-98.7) 94.8 (94.0-95.5) 91.8 (90.7-92.7) 3,244 97.2 (96.6-97.8) 91.2 (90.1-92.2) 87.2 (85.7-88.5) 2,252 99.5 (99.1-99.8) 99.1 (98.3-99.5) 97.8 (96.5-98.7)
40+ 9,571 94.9 (94.4-95.4) 90.9 (90.0-91.7) 87.7 (86.4-88.9) 5,801 93.0 (92.3-93.7) 86.6 (85.5-87.7) 83.0 (81.4-84.4) 4,602 96.7 (96.0-97.3) 95.2 (94.0-96.2) 92.9 (90.8-94.4)
All ages 17,067 96.0 (95.7-96.4) 90.5 (89.9-91.0) 86.6 (85.8-87.4) 11,622 94.6 (94.1-95.0) 85.7 (84.9-86.4) 80.6 (79.7-81.6) 7,135 97.7 (97.3-98.1) 96.6 (95.8-97.2) 94.7 (93.4-95.8)
Glioma malignant, NOS 0-14 6,223 81.3 (80.3-82.3) 68.9 (67.7-70.1) 67.9 (66.6-69.1) 7,164 80.6 (79.7-81.5) 67.7 (66.6-68.9) 66.6 (65.5-67.8) -- -- -- --
15-39 3,805 91.3 (90.4-92.2) 78.7 (77.2-80.1) 72.1 (70.3-73.9) 4,316 90.9 (90.0-91.7) 77.7 (76.3-79.0) 70.9 (69.2-72.5) -- -- -- --
40+ 8,027 53.0 (51.8-54.1) 35.7 (34.5-36.9) 29.8 (28.5-31.2) 9,359 51.5 (50.4-52.5) 34.1 (33.0-35.2) 28.4 (27.2-29.6) -- -- -- --
All ages 18,055 71.0 (70.3-71.7) 56.5 (55.7-57.3) 52.4 (51.5-53.2) 20,839 69.8 (69.2-70.5) 55.0 (54.3-55.8) 50.9 (50.1-51.7) -- -- -- --
Other neuroepithelial tumors 0-14 64 98.5 (89.0-99.8) 91.4 (80.4-96.4) 91.4 (80.4-96.4) 55 98.2 (87.4-99.8) 89.9 (77.3-95.7) 89.9 (77.3-95.7) -- -- -- --
15-39 86 96.5 (89.2-98.9) 88.2 (78.1-93.8) 83.9 (70.9-91.4) 66 95.5 (86.3-98.5) 86.7 (74.7-93.3) 78.8 (63.4-88.3) -- -- -- --
40+ 109 74.3 (64.6-81.8) 52.5 (41.0-62.7) 41.5 (28.8-53.7) 56 69.0 (54.7-79.6) 41.2 (26.8-55.1) 31.6 (17.6-46.5) 63 80.6 (67.5-88.8) 59.4 (43.3-72.2) 51.2 (33.2-66.6)
All ages 259 87.8 (83.0-91.4) 74.6 (68.1-80.0) 68.8 (61.1-75.3) 177 88.0 (82.0-92.1) 73.5 (65.6-79.8) 67.2 (58.2-74.7) 106 88.7 (80.4-93.6) 76.0 (65.1-84.0) 72.1 (59.7-81.3)
Neuronal and mixed neuronal-glial tumors 0-14 3,337 98.8 (98.3-99.1) 96.1 (95.3-96.8) 95.3 (94.4-96.1) 293 92.4 (88.7-95.0) 81.0 (75.8-85.2) 79.5 (74.1-84.0) 3,097 99.3 (98.9-99.6) 97.4 (96.6-97.9) 96.5 (95.6-97.3)
15-39 5,108 98.4 (98.0-98.8) 95.6 (94.9-96.2) 92.7 (91.7-93.7) 593 94.4 (92.1-96.0) 79.3 (75.5-82.6) 70.3 (65.6-74.4) 4,592 98.9 (98.5-99.2) 97.6 (97.0-98.1) 95.6 (94.7-96.4)
40+ 4,029 93.4 (92.5-94.2) 85.2 (83.7-86.5) 80.2 (78.1-82.1) 1,637 90.5 (88.8-91.9) 77.7 (75.1-80.1) 69.2 (65.6-72.4) 2,592 94.7 (93.7-95.6) 89.4 (87.7-90.9) 85.9 (83.4-88.0)
All ages 12,474 96.9 (96.6-97.2) 92.4 (91.8-93.0) 89.4 (88.6-90.2) 2,523 91.6 (90.4-92.7) 78.5 (76.5-80.3) 70.8 (68.3-73.2) 10,281 98.0 (97.7-98.3) 95.5 (94.9-96.0) 93.5 (92.7-94.2)
Choroid plexus tumors 0-14 948 95.9 (94.3-97.0) 90.0 (87.7-91.8) 88.0 (85.4-90.1) 276 87.9 (83.4-91.3) 65.7 (59.3-71.3) 59.8 (52.9-66.1) 710 98.3 (96.9-99.1) 97.2 (95.5-98.3) 96.6 (94.6-97.8)
15-39 593 98.2 (96.7-99.0) 95.9 (93.7-97.4) 92.7 (89.3-95.0) -- -- -- -- 554 98.2 (96.6-99.1) 97.0 (95.0-98.2) 95.5 (92.4-97.4)
40+ 696 89.5 (86.8-91.7) 84.9 (81.1-88.0) 79.1 (73.4-83.6) -- -- -- -- 647 90.5 (87.8-92.7) 86.5 (82.6-89.6) 81.5 (75.5-86.1)
All ages 2,237 94.5 (93.4-95.5) 90.0 (88.4-91.3) 86.6 (84.5-88.5) 373 87.2 (83.2-90.3) 67.3 (61.9-72.1) 58.5 (52.3-64.1) 1,911 95.7 (94.6-96.6) 93.7 (92.2-94.9) 91.4 (89.3-93.2)
Tumors of the pineal region 0-14 384 88.8 (85.1-91.6) 67.5 (62.1-72.2) 61.4 (55.5-66.8) 377 85.6 (81.5-88.8) 60.9 (55.4-65.9) 53.8 (47.9-59.4) 61 98.4 (88.5-99.8) 98.4 (88.5-99.8) 95.6 (81.6-99.0)
15-39 712 95.5 (93.6-96.8) 87.2 (84.1-89.7) 81.9 (78.0-85.2) 427 93.6 (90.8-95.6) 75.7 (70.7-79.9) 66.3 (60.3-71.5) 339 97.1 (94.5-98.5) 96.8 (93.8-98.3) 94.9 (90.6-97.3)
40+ 762 90.4 (87.9-92.4) 80.0 (76.2-83.2) 69.8 (64.4-74.6) 352 86.6 (82.3-89.9) 69.1 (63.0-74.3) 56.0 (48.4-62.9) 443 92.5 (89.3-94.8) 87.3 (82.5-90.8) 79.7 (72.4-85.3)
All ages 1,858 92.0 (90.6-93.2) 80.1 (77.9-82.1) 72.8 (69.9-75.5) 1,156 88.9 (86.8-90.6) 68.8 (65.7-71.6) 59.2 (55.5-62.6) 843 94.8 (92.9-96.2) 92.0 (89.3-94.0) 87.3 (83.3-90.5)
Embryonal tumors 0-14 6,023 82.0 (81.0-83.0) 64.1 (62.8-65.4) 59.0 (57.6-60.4) 7,125 81.6 (80.7-82.5) 63.2 (62.0-64.4) 58.2 (57.0-59.5) -- -- -- --
15-39 2,133 91.4 (90.1-92.6) 71.9 (69.8-73.9) 61.7 (59.2-64.2) 2,571 90.7 (89.5-91.8) 71.1 (69.2-73.0) 61.2 (59.0-63.3) -- -- -- --
40+ 773 70.0 (66.5-73.1) 46.0 (42.1-49.7) 37.5 (33.2-41.7) 899 70.0 (66.8-72.9) 46.6 (43.0-50.0) 37.5 (33.7-41.3) -- -- -- --
All ages 8,929 83.2 (82.4-84.0) 64.4 (63.3-65.4) 57.7 (56.5-58.9) 10,595 82.8 (82.1-83.5) 63.7 (62.7-64.7) 57.2 (56.1-58.2) -- -- -- --
Nerve sheath tumors 0-14 2,251 99.8 (99.4-99.9) 98.9 (98.2-99.3) 98.0 (97.2-98.6) -- -- -- -- 2,216 100.0 (0.0-100.0) 99.3 (98.7-99.6) 98.5 (97.7-99.0)
15-39 13,549 99.3 (99.1-99.4) 98.5 (98.2-98.7) 97.6 (97.1-98.0) -- -- -- -- 13,406 99.5 (99.3-99.6) 98.8 (98.5-99.0) 98.0 (97.6-98.4)
40+ 73,152 99.2 (99.1-99.3) 99.2 (99.1-99.3) 99.2 (99.1-99.3) 496 86.2 (82.6-89.1) 76.9 (72.2-80.9) 72.9 (66.6-78.2) 72,783 99.3 (99.1-99.4) 99.3 (99.1-99.4) 99.3 (99.1-99.4)
All ages 88,952 99.2 (99.1-99.3) 99.2 (99.1-99.3) 99.2 (99.1-99.3) 720 85.0 (82.0-87.5) 74.8 (71.0-78.1) 70.0 (65.3-74.2) 88,405 99.3 (99.2-99.4) 99.3 (99.2-99.4) 99.3 (99.2-99.4)
Other tumors of cranial and spinal nerves 0-14 -- -- -- -- -- -- -- -- -- -- -- --
15-39 -- -- -- -- -- -- -- -- -- -- -- --
40+ 56 97.8 (79.9-99.8) 96.1 (75.2-99.4) 91.5 (62.2-98.4) -- -- -- -- 56 97.8 (79.9-99.8) 96.1 (75.2-99.4) 91.5 (62.2-98.4)
All ages 69 96.7 (85.4-99.3) 93.8 (80.4-98.1) 90.2 (69.6-97.1) -- -- -- -- 69 96.7 (85.4-99.3) 93.8 (80.4-98.1) 90.2 (69.6-97.1)
Meningiomas 0-14 688 97.8 (96.3-98.7) 95.4 (93.4-96.8) 92.0 (89.1-94.2) 60 90.0 (78.9-95.4) 79.6 (66.8-87.9) 74.8 (60.8-84.5) 639 98.6 (97.3-99.3) 96.5 (94.6-97.8) 93.4 (90.4-95.4)
15-39 24,271 98.8 (98.6-98.9) 97.0 (96.8-97.3) 94.9 (94.5-95.3) 420 93.8 (91.0-95.8) 84.4 (80.3-87.8) 78.7 (73.7-82.8) 23,943 98.9 (98.7-99.0) 97.2 (97.0-97.5) 95.2 (94.8-95.6)
40+ 372,963 92.9 (92.8-93.0) 87.4 (87.2-87.5) 82.2 (82.0-82.5) 4,678 83.1 (81.9-84.2) 65.1 (63.4-66.8) 58.0 (55.9-60.1) 369,249 93.0 (92.9-93.1) 87.6 (87.4-87.8) 82.5 (82.2-82.8)
All ages 397,922 93.2 (93.1-93.3) 88.0 (87.8-88.2) 83.2 (82.9-83.4) 5,158 84.1 (82.9-85.1) 67.0 (65.4-68.5) 60.1 (58.1-62.0) 393,831 93.3 (93.2-93.4) 88.3 (88.1-88.4) 83.4 (83.2-83.7)
Mesenchymal tumors 0-14 1,285 97.8 (96.8-98.5) 94.3 (92.7-95.5) 92.4 (90.3-94.0) 200 85.7 (80.0-89.9) 69.1 (61.7-75.3) 62.1 (54.1-69.1) 1,118 99.4 (98.6-99.8) 97.7 (96.5-98.6) 96.5 (94.5-97.7)
15-39 4,428 98.2 (97.7-98.6) 95.8 (95.0-96.4) 93.6 (92.5-94.5) 545 91.9 (89.2-93.9) 79.8 (75.9-83.1) 71.7 (67.0-75.9) 3,989 98.9 (98.5-99.2) 97.5 (96.8-98.0) 95.8 (94.8-96.7)
40+ 10,582 94.2 (93.7-94.7) 89.2 (88.3-90.0) 84.1 (82.7-85.4) 1,324 87.4 (85.3-89.2) 69.1 (66.0-72.0) 52.4 (48.3-56.2) 9,453 95.0 (94.5-95.5) 91.6 (90.7-92.4) 87.8 (86.3-89.0)
All ages 16,295 95.6 (95.2-95.9) 91.4 (90.8-92.0) 87.4 (86.5-88.3) 2,069 88.4 (86.9-89.8) 72.1 (69.8-74.3) 59.0 (56.1-61.8) 14,560 96.4 (96.1-96.8) 93.7 (93.1-94.2) 90.7 (89.7-91.6)
Primary melanocytic lesions 0-14 -- -- -- -- -- -- -- -- -- -- -- --
15-39 -- -- -- -- -- -- -- -- -- -- -- --
40+ 191 70.2 (62.7-76.4) 47.1 (38.2-55.4) 31.3 (21.4-41.7) 133 61.8 (52.6-69.8) 34.2 (25.0-43.6) 20.5 (11.6-31.1) 76 86.1 (74.7-92.6) 63.6 (47.6-75.9) 44.9 (27.7-60.7)
All ages 263 69.3 (63.0-74.7) 49.5 (42.2-56.4) 35.9 (27.7-44.1) 186 58.9 (51.3-65.8) 35.2 (27.5-43.0) 23.5 (15.7-32.3) 102 87.6 (78.5-93.0) 70.5 (57.8-80.0) 55.0 (39.7-67.8)
Lymphoma 0-14 176 91.8 (86.5-95.1) 86.5 (80.2-91.0) 80.5 (72.1-86.6) 197 91.7 (86.7-94.8) 86.4 (80.4-90.6) 81.7 (74.3-87.1) -- -- -- --
15-39 1,554 67.7 (65.3-70.0) 59.6 (57.0-62.1) 55.4 (52.5-58.2) 1,923 63.4 (61.2-65.5) 54.6 (52.3-56.9) 50.7 (48.2-53.1) -- -- -- --
40+ 15,460 54.4 (53.6-55.3) 36.6 (35.7-37.5) 28.4 (27.4-29.5) 17,909 53.7 (53.0-54.5) 35.2 (34.4-36.1) 26.6 (25.7-27.6) -- -- -- --
All ages 17,190 56.1 (55.3-56.8) 39.4 (38.6-40.2) 31.8 (30.8-32.7) 20,029 55.1 (54.3-55.8) 37.8 (37.0-38.5) 29.8 (29.0-30.7) -- -- -- --
Other hematopoietic neoplasms 0-14 -- -- -- -- -- -- -- -- -- -- -- --
15-39 -- -- -- -- -- -- -- -- -- -- -- --
40+ 141 83.1 (75.3-88.6) 67.0 (57.0-75.1) 63.2 (51.6-72.7) 174 82.5 (75.6-87.6) 64.4 (55.7-71.9) 59.9 (50.0-68.5) -- -- -- --
All ages 157 84.8 (77.7-89.8) 67.4 (58.1-75.1) 64.0 (53.3-72.9) 197 84.6 (78.3-89.1) 66.4 (58.3-73.3) 62.6 (53.5-70.4) -- -- -- --
Germ cell tumors 0-14 1,414 93.5 (92.0-94.7) 89.5 (87.6-91.0) 86.7 (84.5-88.7) 1,429 93.0 (91.5-94.2) 87.8 (85.9-89.4) 84.3 (82.0-86.3) 186 92.6 (87.6-95.6) 92.0 (86.9-95.2) 92.0 (86.9-95.2)
15-39 1,548 95.4 (94.2-96.4) 89.6 (87.7-91.1) 87.1 (85.0-89.0) 1,653 94.5 (93.3-95.5) 88.6 (86.8-90.1) 85.9 (83.8-87.7) 127 99.3 (93.4-99.9) 93.3 (86.2-96.8) 91.1 (83.0-95.4)
40+ 196 92.5 (87.3-95.7) 83.2 (75.5-88.6) 78.6 (69.7-85.2) 87 81.7 (71.3-88.6) 63.5 (51.1-73.6) 60.0 (45.7-71.6) 124 98.5 (90.2-99.8) 93.4 (82.7-97.6) 86.8 (74.4-93.4)
All ages 3,158 94.3 (93.5-95.1) 89.1 (87.9-90.3) 86.5 (84.9-87.8) 3,169 93.5 (92.6-94.3) 87.5 (86.2-88.7) 84.5 (82.9-85.9) 437 96.2 (93.7-97.7) 92.7 (89.2-95.1) 90.2 (85.9-93.3)
Tumors of the pituitary 0-14 2,564 99.8 (99.5-99.9) 99.4 (98.9-99.7) 99.0 (98.2-99.4) -- -- -- -- 2,562 99.8 (99.5-99.9) 99.4 (98.9-99.7) 99.0 (98.2-99.4)
15-39 55,228 99.7 (99.7-99.8) 99.4 (99.3-99.5) 98.9 (98.7-99.0) -- -- -- -- 55,155 99.7 (99.7-99.8) 99.4 (99.3-99.5) 98.9 (98.7-99.1)
40+ 121,454 97.5 (97.4-97.7) 95.9 (95.6-96.1) 93.4 (93.0-93.8) 371 88.4 (84.3-91.5) 79.4 (73.6-84.1) 70.0 (62.2-76.5) 121,153 97.6 (97.5-97.7) 95.9 (95.7-96.1) 93.5 (93.1-93.9)
All ages 179,246 98.3 (98.2-98.3) 97.0 (96.9-97.2) 95.3 (95.0-95.6) 476 90.6 (87.3-93.1) 81.9 (77.2-85.7) 74.7 (68.4-79.9) 178,870 98.3 (98.2-98.4) 97.1 (96.9-97.2) 95.3 (95.1-95.6)
Craniopharyngioma 0-14 1,860 98.6 (98.0-99.1) 95.8 (94.6-96.7) 91.8 (90.1-93.3) -- -- -- -- 1,851 98.7 (98.0-99.1) 95.8 (94.7-96.7) 91.9 (90.1-93.3)
15-39 1,920 96.3 (95.3-97.0) 91.5 (90.0-92.8) 87.6 (85.6-89.3) -- -- -- -- 1,918 96.2 (95.3-97.0) 91.6 (90.1-92.9) 87.7 (85.7-89.4)
40+ 4,386 88.9 (87.9-89.9) 78.5 (76.9-80.0) 69.9 (67.7-71.9) -- -- -- -- 4,377 89.0 (87.9-89.9) 78.5 (77.0-80.0) 69.9 (67.7-72.0)
All ages 8,166 92.9 (92.3-93.5) 85.7 (84.7-86.5) 79.5 (78.2-80.7) -- -- -- -- 8,146 92.9 (92.3-93.5) 85.7 (84.8-86.6) 79.5 (78.2-80.8)
Hemangioma 0-14 598 99.4 (98.2-99.8) 98.0 (96.4-98.9) 98.0 (96.4-98.9) -- -- -- -- 598 99.4 (98.2-99.8) 98.0 (96.4-98.9) 98.0 (96.4-98.9)
15-39 2,725 99.6 (99.2-99.8) 98.7 (97.9-99.1) 97.1 (95.8-98.0) -- -- -- -- 2,719 99.6 (99.3-99.8) 98.7 (98.0-99.2) 97.1 (95.8-98.0)
40+ 5,577 96.1 (95.4-96.6) 91.8 (90.6-92.9) 89.4 (87.3-91.1) -- -- -- -- 5,570 96.1 (95.4-96.7) 91.9 (90.7-93.0) 89.4 (87.4-91.2)
All ages 8,900 97.4 (97.0-97.8) 94.4 (93.6-95.1) 92.5 (91.3-93.6) -- -- -- -- 8,887 97.4 (97.0-97.8) 94.5 (93.7-95.2) 92.6 (91.3-93.7)
Neoplasm, unspecified 0-14 1,460 88.5 (86.7-90.0) 85.5 (83.5-87.2) 84.0 (81.9-86.0) 396 66.3 (61.4-70.8) 58.0 (52.8-62.8) 54.8 (49.4-59.9) 1,108 95.3 (93.9-96.5) 94.2 (92.6-95.5) 93.4 (91.5-94.9)
15-39 4,268 93.5 (92.7-94.2) 90.2 (89.2-91.1) 87.9 (86.7-89.0) 869 79.3 (76.4-81.9) 68.6 (65.2-71.7) 63.2 (59.4-66.7) 3,560 96.1 (95.4-96.7) 94.1 (93.2-94.9) 92.3 (91.1-93.3)
40+ 21,433 54.4 (53.7-55.1) 45.3 (44.5-46.1) 40.2 (39.2-41.1) 9,806 27.3 (26.4-28.3) 17.7 (16.9-18.6) 15.2 (14.3-16.2) 13,267 71.4 (70.6-72.2) 62.3 (61.3-63.3) 55.7 (54.4-57.0)
All ages 27,161 62.6 (62.0-63.2) 54.9 (54.2-55.6) 50.6 (49.8-51.4) 11,071 33.0 (32.1-34.0) 23.5 (22.6-24.3) 20.7 (19.7-21.6) 17,935 77.9 (77.3-78.6) 70.9 (70.1-71.7) 65.9 (64.9-66.9)
All other 0-14 416 89.9 (86.5-92.5) 85.0 (81.0-88.2) 85.0 (81.0-88.2) 124 60.5 (51.1-68.5) 39.7 (30.6-48.8) 38.2 (29.0-47.4) 310 99.5 (97.0-99.9) 99.5 (97.0-99.9) 99.5 (97.0-99.9)
15-39 368 98.1 (96.0-99.1) 94.5 (91.2-96.6) 92.9 (88.7-95.7) -- -- -- -- 335 99.2 (97.1-99.8) 97.9 (94.9-99.1) 96.2 (91.7-98.3)
40+ 572 87.6 (84.2-90.3) 83.8 (78.7-87.7) 74.4 (67.0-80.4) -- -- -- -- 548 88.9 (85.4-91.6) 85.5 (80.3-89.4) 76.1 (68.3-82.2)
All ages 1,356 91.2 (89.4-92.7) 87.1 (84.7-89.2) 83.3 (80.0-86.1) 194 65.9 (58.6-72.2) 43.8 (36.2-51.2) 40.8 (32.9-48.6) 1,193 94.6 (92.9-95.9) 92.8 (90.3-94.6) 88.6 (85.1-91.4)
TOTAL i 0-14 46,102 91.6 (91.4-91.9) 83.2 (82.8-83.6) 80.7 (80.2-81.1) 35,281 87.4 (87.1-87.8) 75.0 (74.6-75.5) 71.8 (71.3-72.3) 16,035 98.9 (98.8-99.1) 97.6 (97.3-97.8) 96.4 (96.0-96.7)
15-39 157,627 97.0 (96.9-97.1) 91.1 (90.9-91.2) 87.1 (86.9-87.3) 52,117 90.7 (90.5-91.0) 71.9 (71.5-72.3) 61.5 (61.0-62.0) 113,601 99.3 (99.2-99.3) 98.4 (98.3-98.4) 97.2 (97.0-97.3)
40+ 805,163 83.2 (83.1-83.3) 72.8 (72.7-72.9) 68.9 (68.7-69.0) 232,885 49.4 (49.2-49.6) 21.1 (20.9-21.3) 16.8 (16.6-17.0) 605,615 94.2 (94.2-94.3) 90.4 (90.3-90.5) 86.8 (86.6-87.0)
All ages 1,008,892 85.8 (85.7-85.9) 76.3 (76.1-76.4) 72.4 (72.3-72.6) 320,283 60.4 (60.3-60.6) 35.7 (35.5-35.9) 30.6 (30.4-30.8) 735,251 95.1 (95.1-95.2) 91.9 (91.7-92.0) 88.8 (88.6-88.9)

aThe cohort analysis of survival rates was utilized for calculating the survival estimates presented in this table. Long-term cohort-based survival estimates reflect the survival experience of individuals diagnosed over the time periods, and they may not necessarily reflect the long-term survival outlook of newly diagnosed cases.

bRates are an estimate of the percentage of cases alive at one, two, five, and ten years, respectively. Rates were not presented for categories with 50 or fewer cases and were suppressed for rates where fewer than 16 cases were surviving within a category.

cAssigned behavior code of /3 (see Tables 2).

dAssigned behavior code of /0 or /1 (see Table 2).

eTotal number of cases that occurred within the included NPCR and SEER registries between 2004 and 2019.

fTotal number of cases that occurred within the included NPCR and SEER registries between 2001 and 2019.

gChildren as defined by the National Cancer Institute, see: http://www.cancer.gov/researchandfunding/snapshots/pediatric.

hAdolescents and Young Adults (AYA), as defined by the National Cancer Institute, see: http://www.cancer.gov/cancertopics/aya.

i Total includes histopathologies not listed in this table.

- Rates were not presented for categories with 50 or fewer cases and were suppressed for rates where fewer than 16 cases were surviving within a category.

** Confidence interval could not be calculated.

Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; CI, confidence interval; NOS, not otherwise specified; RS, Relative survival.