Table 17.
Five-Year Total, Annual Average Totala, and Average Annual Age-Adjusted Incidence Ratesb with 95% Confidence Intervals for Children and Adolescents (Ages 0-19 Years) by Histopathology and Racec, CBTRUS Statistical Report: US Cancer Statistics – NPCR and SEER, 2016-2020
| Histopathology | White | Black | American Indian/Alaska Native | Asian/Pacific Islander | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5-Year Total | Annual Average | Rate (95% CI) | 5-Year Total | Annual Average | Rate (95% CI) | 5-Year Total | Annual Average | Rate (95% CI) | 5-Year Total | Annual Average | Rate (95% CI) | |
| Diffuse Astrocytic and Oligodendroglial Tumors | 1,505 | 301 | 0.49 (0.47-0.52) | 236 | 47 | 0.35 (0.30-0.39) | 17 | 3 | 0.22 (0.13-0.35) | 69 | 14 | 0.26 (0.20-0.33) |
| Diffuse astrocytoma | 638 | 128 | 0.21 (0.19-0.23) | 92 | 18 | 0.13 (0.11-0.16) | -- | -- | -- | 23 | 5 | 0.08 (0.05-0.13) |
| Anaplastic astrocytoma | 241 | 48 | 0.08 (0.07-0.09) | 34 | 7 | 0.05 (0.03-0.07) | -- | -- | -- | -- | -- | -- |
| Glioblastoma | 493 | 99 | 0.16 (0.15-0.18) | 92 | 18 | 0.14 (0.11-0.17) | -- | -- | -- | 30 | 6 | 0.11 (0.08-0.16) |
| Oligodendroglioma | 104 | 21 | 0.03 (0.03-0.04) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Anaplastic oligodendroglioma | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Oligoastrocytic tumors | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Other Astrocytic Tumors | 3,522 | 704 | 1.17 (1.13-1.21) | 558 | 112 | 0.81 (0.75-0.88) | 47 | 9 | 0.59 (0.43-0.79) | 115 | 23 | 0.42 (0.34-0.50) |
| Pilocytic astrocytoma | 3,147 | 629 | 1.04 (1.01-1.08) | 487 | 97 | 0.71 (0.65-0.77) | -- | -- | -- | 96 | 19 | 0.35 (0.28-0.43) |
| Unique astrocytoma variants | 375 | 75 | 0.12 (0.11-0.14) | 71 | 14 | 0.10 (0.08-0.13) | -- | -- | -- | 19 | 4 | 0.07 (0.04-0.11) |
| Malignant | 168 | 34 | 0.05 (0.05-0.06) | 24 | 5 | 0.04 (0.02-0.05) | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 207 | 41 | 0.07 (0.06-0.08) | 47 | 9 | 0.07 (0.05-0.09) | -- | -- | -- | -- | -- | -- |
| Ependymal Tumors | 907 | 181 | 0.30 (0.28-0.32) | 145 | 29 | 0.21 (0.18-0.25) | -- | -- | -- | 46 | 9 | 0.16 (0.12-0.22) |
| Malignant | 716 | 143 | 0.24 (0.22-0.26) | 128 | 26 | 0.18 (0.15-0.22) | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 191 | 38 | 0.06 (0.05-0.07) | 17 | 3 | 0.02 (0.01-0.04) | -- | -- | -- | -- | -- | -- |
| Other Gliomas | 2,443 | 489 | 0.81 (0.78-0.84) | 453 | 91 | 0.66 (0.60-0.72) | 29 | 6 | 0.37 (0.25-0.53) | 112 | 22 | 0.41 (0.34-0.49) |
| Glioma malignant, NOS | 2,426 | 485 | 0.81 (0.77-0.84) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Other neuroepithelial tumors | 17 | 3 | 0.01 (0.00-0.01) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Neuronal and Mixed Neuronal-Glial Tumors | 1,636 | 327 | 0.54 (0.51-0.56) | 270 | 54 | 0.39 (0.35-0.45) | 20 | 4 | 0.26 (0.16-0.40) | 82 | 16 | 0.31 (0.24-0.38) |
| Malignant | 105 | 21 | 0.03 (0.03-0.04) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 1,531 | 306 | 0.50 (0.48-0.53) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Choroid Plexus Tumors | 316 | 63 | 0.11 (0.09-0.12) | 45 | 9 | 0.06 (0.05-0.09) | -- | -- | -- | -- | -- | -- |
| Malignant | 72 | 14 | 0.02 (0.02-0.03) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 244 | 49 | 0.08 (0.07-0.09) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of The Pineal Region | 141 | 28 | 0.05 (0.04-0.05) | 50 | 10 | 0.07 (0.05-0.10) | -- | -- | -- | -- | -- | -- |
| Malignant | 113 | 23 | 0.04 (0.03-0.04) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 28 | 6 | 0.01 (0.01-0.01) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Embryonal Tumors | 1,762 | 352 | 0.59 (0.56-0.62) | 272 | 54 | 0.39 (0.35-0.44) | 23 | 5 | 0.29 (0.18-0.43) | 112 | 22 | 0.40 (0.33-0.48) |
| Medulloblastoma | 1,248 | 250 | 0.42 (0.39-0.44) | 171 | 34 | 0.25 (0.21-0.29) | 19 | 4 | 0.24 (0.14-0.37) | 81 | 16 | 0.29 (0.23-0.36) |
| Atypical teratoid/rhabdoid tumor | 267 | 53 | 0.09 (0.08-0.10) | 49 | 10 | 0.07 (0.05-0.09) | -- | -- | -- | -- | -- | -- |
| All other embryonal | 247 | 49 | 0.08 (0.07-0.09) | 52 | 10 | 0.07 (0.06-0.10) | -- | -- | -- | -- | -- | -- |
| Tumors of Cranial and Spinal Nerves | 806 | 161 | 0.26 (0.25-0.28) | 117 | 23 | 0.17 (0.14-0.20) | -- | -- | -- | 34 | 7 | 0.13 (0.09-0.18) |
| Nerve sheath tumors | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Other tumors of cranial and spinal nerves | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of Meninges | 952 | 190 | 0.31 (0.29-0.33) | 183 | 37 | 0.27 (0.23-0.31) | -- | -- | -- | 38 | 8 | 0.14 (0.10-0.19) |
| Meningiomas | 504 | 101 | 0.16 (0.15-0.18) | 112 | 22 | 0.16 (0.14-0.20) | -- | -- | -- | 17 | 3 | 0.06 (0.04-0.10) |
| Mesenchymal tumors | -- | -- | --) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Primary melanocytic lesions | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Lymphomas and Hematopoietic Neoplasms | 92 | 18 | 0.03 (0.02-0.04) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Lymphoma | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Other hematopoietic neoplasms | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Germ Cell Tumors | 613 | 123 | 0.20 (0.19-0.22) | 104 | 21 | 0.15 (0.12-0.18) | -- | -- | -- | 93 | 19 | 0.35 (0.28-0.43) |
| Malignant | 547 | 109 | 0.18 (0.16-0.19) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 66 | 13 | 0.02 (0.02-0.03) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of Sellar Region | 3,499 | 700 | 1.13 (1.09-1.17) | 657 | 131 | 0.96 (0.89-1.04) | 54 | 11 | 0.71 (0.53-0.92) | 164 | 33 | 0.62 (0.52-0.72) |
| Tumors of the pituitary | 2,938 | 588 | 0.94 (0.91-0.98) | 529 | 106 | 0.78 (0.71-0.85) | -- | -- | -- | 131 | 26 | 0.49 (0.41-0.59) |
| Craniopharyngioma | 561 | 112 | 0.19 (0.17-0.20) | 128 | 26 | 0.19 (0.16-0.22) | -- | -- | -- | 33 | 7 | 0.12 (0.08-0.17) |
| Unclassified Tumors | 1,135 | 227 | 0.37 (0.35-0.40) | 179 | 36 | 0.26 (0.22-0.30) | -- | -- | -- | 35 | 7 | 0.13 (0.09-0.18) |
| Hemangioma | 396 | 79 | 0.13 (0.12-0.14) | 47 | 9 | 0.07 (0.05-0.09) | -- | -- | -- | -- | -- | -- |
| Neoplasm, unspecified | 597 | 119 | 0.20 (0.18-0.21) | 104 | 21 | 0.15 (0.12-0.18) | -- | -- | -- | 17 | 3 | 0.06 (0.04-0.10) |
| Malignant | 164 | 33 | 0.05 (0.05-0.06) | 39 | 8 | 0.06 (0.04-0.08) | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 433 | 87 | 0.14 (0.13-0.16) | 65 | 13 | 0.10 (0.07-0.12) | -- | -- | -- | -- | -- | -- |
| All other | 142 | 28 | 0.05 (0.04-0.06) | 28 | 6 | 0.04 (0.03-0.06) | -- | -- | -- | -- | -- | -- |
| Malignant | 29 | 6 | 0.01 (0.01-0.01) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 113 | 23 | 0.04 (0.03-0.05) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| TOTAL d | 19,329 | 3,866 | 6.36 (6.27-6.45) | 3,284 | 657 | 4.79 (4.62-4.95) | 244 | 49 | 3.12 (2.74-3.54) | 925 | 185 | 3.40 (3.19-3.63) |
| Malignant | 10,759 | 2,152 | 3.56 (3.50-3.63) | 1,824 | 365 | 2.65 (2.53-2.78) | 125 | 25 | 1.58 (1.32-1.888) | 541 | 108 | 1.97 (1.81-2.15) |
| Non-Malignant | 8,570 | 1,714 | 2.79 (2.73-2.85) | 1,460 | 292 | 2.14 (2.03-2.25) | 119 | 24 | 1.54 (1.27-1.84) | 384 | 77 | 1.43 (1.29-1.58) |
aAnnual average cases are calculated by dividing the five-year total by five.
bRates are per 100,000 and are age-adjusted to the 2000 US standard population.
cIndividuals with unknown race were excluded (N = 1,217).
d Refers to all brain tumors including histopathologies not presented in this table.
- Counts and rates are not presented when fewer than 16 cases were reported for the specific category. The suppressed cases are included in the counts and rates for totals.
Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program; CI, confidence interval; NOS, not otherwise specified