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. 2023 Oct 4;25(Suppl 4):iv1–iv99. doi: 10.1093/neuonc/noad149

Table 7.

Five-Year Total, Annual Average Totala, and Average Annual Age-Adjusted Incidence Ratesb with 95% Confidence Intervals for Selected Non-Malignant Histopathologies by Sex, Age Groups, Race, and Hispanic Ethnicity, Histopathology, and Age at Diagnosis, CBTRUS Statistical Report: US Cancer Statistics – NPCR and SEER, 2016-2020

Group Vestibular Schwannomac Pituitary Adenomad WHO Grade I Meningiomae WHO Grade II Meningiomaf
5-Year Total Annual Average Rate (95% CI) 5-Year Total Annual Average Rate (95% CI) 5-Year Total Annual Average Rate (95% CI) 5-Year Total Annual Average Rate (95% CI)
Sex
Male 13,107 2,621 1.48 (1.45-1.50) 30,296 6,059 3.51 (3.47-3.55) 20,158 4,032 2.29 (2.25-2.32) 4,144 829 0.47 (0.46-0.49)
Female 14,590 2,918 1.52 (1.49-1.55) 38,364 7,673 4.51 (4.47-4.56) 54,441 10,888 5.49 (5.45-5.54) 5,843 1,169 0.61 (0.60-0.63)
Age Groups
0-14 years 198 40 0.07 (0.06-0.08) 989 198 0.33 (0.31-0.35) 110 22 0.04 (0.03-0.04) 83 17 0.03 (0.02-0.03)
15-39 years 3,632 726 0.69 (0.67-0.71) 19,705 3,941 3.64 (3.59-3.69) 5,158 1,032 1.01 (0.98-1.04) 1,124 225 0.22 (0.20-0.23)
40-64 years 14,070 2,814 2.53 (2.49-2.58) 28,540 5,708 5.47 (5.40-5.54) 32,676 6,535 5.86 (5.79-5.92) 4,657 931 0.85 (0.82-0.87)
65+ years 9,797 1,959 3.71 (3.63-3.78) 19,426 3,885 7.49 (7.39-7.60) 36,655 7,331 14.37 (14.22-14.52) 4,123 825 1.60 (1.55-1.65)
Race
White 23,592 4,718 1.58 (1.56-1.60) 48,528 9,706 3.56 (3.52-3.59) 59,793 11,959 3.88 (3.85-3.91) 7,578 1,516 0.51 (0.50-0.52)
Black 1,602 320 0.72 (0.68-0.75) 14,032 2,806 6.38 (6.28-6.49) 9,715 1,943 4.51 (4.42-4.61) 1,591 318 0.71 (0.68-0.75)
American Indian/Alaska Native 163 33 0.75 (0.63-0.87) 608 122 2.78 (2.55-3.02) 524 105 2.69 (2.46-2.94) 56 11 0.29 (0.22-0.38)
Asian or Pacific Islander 1,373 275 1.23 (1.16-1.29) 2,932 586 2.67 (2.58-2.77) 2,745 549 2.56 (2.46-2.66) 506 101 0.47 (0.43-0.51)
Ethnicity
Non-Hispanic 25,235 5,047 1.58 (1.56-1.60) 57,030 11,406 3.89 (3.86-3.92) 67,178 13,436 4.06 (4.03-4.09) 8,946 1,789 0.56 (0.55-0.57)
Hispanic 2,412 482 0.99 (0.95-1.03) 11,515 2,303 4.45 (4.37-4.54) 7,248 1,450 3.27 (3.19-3.35) 1,026 205 0.44 (0.42-0.47)
TOTAL 27,697 5,539 1.50 (1.48-1.51) 68,660 13,732 3.97 (3.94-4.00) 74,599 14,920 3.96 (3.93-3.99) 9,987 1,997 0.54 (0.53-0.55)

aAnnual average cases are calculated by dividing the five-year total by five.

bRates are per 100,000 and are age-adjusted to the 2000 US standard population.

cICD-O-3 histopathology code 9560/0 and ICD-O-3 topography code C72.4 and C72.5.

dICD-O-3 histopathology code 8272/0 and ICD-O-3 topography code C75.1.

eICD-O-3 histopathology codes 9530/0, 9531/0, 9532/0, 9533/0, 9534/0, and 9537/0.

f ICD-O-3 histopathology codes 9530/1, 9531/1, 9532/1, 9533/1, 9534/1, 9537/1, 9538/1, and 9539/1.

- Counts and rates are not presented when fewer than 16 cases were reported for the specific category. The suppressed cases are included in the counts and rates for totals.

Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; US, United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program; WHO, World Health Organization; CI, confidence interval.