Table 3. Region and gender-wise ASIR of leading HNC sites (2012–2019).
| ICD-10 | Site | Central | East | North | Northeast | South | West | India |
|---|---|---|---|---|---|---|---|---|
| Male | ||||||||
| All | All site (H&N) | 28.3 | 18.3 | 28.5 | 31.7 | 23.9 | 24.4 | 25.9 |
| (27.4–29.2) | (17.5–19.1) | (27.9–29.1) | (31.1–32.3) | (23.5–24.3) | (24.0–24.8) | (25.7–26.1) | ||
| 1 in 31 | 1 in 47 | 1 in 30 | 1 in 26 | 1 in 35 | 1 in 36 | 1 in 33 | ||
| C03-C06 | Mouth | 12.8 | 5.9 | 9.1 | 5.6 | 7.3 | 10.8 | 8.7 |
| (12.2–13.4) | (5.5–6.3) | (8.8–9.4) | (5.3–5.9) | (7.1–7.5) | (10.6–11.0) | (8.6–8.8) | ||
| 1 in 71 | 1 in 147 | 1 in 97 | 1 in 145 | 1 in 121 | 1 in 83 | 1 in 101 | ||
| C01-C02 | Tongue | 6.4 | 4.4 | 7.2 | 5.0 | 6.1 | 5.8 | 5.9 |
| (6.0–6.8) | (4.0–4.8) | (6.9–7.5) | (4.8–5.2) | (5.9–6.3) | (5.6–6.0) | (5.8–6.0) | ||
| 1 in 144 | 1 in 214 | 1 in 120 | 1 in 166 | 1 in 143 | 1 in 156 | 1 in 149 | ||
| C32 | Larynx | 4.3 | 4.3 | 5.7 | 5.2 | 4.3 | 3.2 | 4.3 |
| (3.9–4.7) | (3.9–4.7) | (5.4–6.0) | (4.9–5.5) | (4.1–4.5) | (3.1–3.3) | (4.2–4.4) | ||
| 1 in 178 | 1 in 192 | 1 in 142 | 1 in 156 | 1 in 180 | 1 in 253 | 1 in 185 | ||
| C12-C13 | Hypopharynx | 2.0 | 1.7 | 2.0 | 8.0 | 2.6 | 2.0 | 3.1 |
| (1.8–2.2) | (1.5–1.9) | (1.8–2.2) | (7.7–8.3) | (2.5–2.7) | (1.9–2.1) | (3.0–3.2) | ||
| 1 in 399 | 1 in 480 | 1 in 398 | 1 in 101 | 1 in 310 | 1 in 404 | 1 in 267 | ||
| C09 | Tonsil | 1.1 | 0.6 | 1.7 | 2.4 | 0.8 | 0.7 | 1.2 |
| (0.9–1.3) | (0.5–0.7) | (1.6–1.8) | (2.2–2.6) | (0.7–0.9) | (0.6–0.8) | (1.15–1.25) | ||
| 1 in 727 | 1 in 1,341 | 1 in 493 | 1 in 347 | 1 in 1,093 | 1 in 1,205 | 1 in 721 | ||
| C10 | Other oropharynx | 0.5 | 0.4 | 1.4 | 1.4 | 1.5 | 0.5 | 1.0 |
| (0.4–0.6) | (0.3–0.5) | (1.3–1.5) | (1.3–1.5) | (1.4–1.6) | (0.4–0.6) | (0.96–1.04) | ||
| 1 in 1,687 | 1 in 2,267 | 1 in 564 | 1 in 583 | 1 in 517 | 1 in 1,564 | 1 in 775 | ||
| C11 | Nasopharynx | 0.3 | 0.4 | 0.5 | 2.3 | 0.5 | 0.3 | 0.7 |
| (0.2–0.4) | (0.3–0.5) | (0.4–0.6) | (2.1–2.5) | (0.4–0.6) | (0.26–0.34) | (0.66–0.74) | ||
| 1 in 2,786 | 1 in 1,963 | 1 in 1,940 | 1 in 375 | 1 in 1,907 | 1 in 3,099 | 1 in 1,298 | ||
| C14 | Pharynx unspecified | 0.3 | 0.5 | 0.4 | 1.4 | 0.4 | 0.5 | 0.6 |
| (0.2–0.4) | (0.4–0.6) | (0.3–0.5) | (1.3–1.5) | (0.3–0.5) | (0.4–0.6) | (0.57–0.63) | ||
| 1 in 2,546 | 1 in 2,010 | 1 in 2,107 | 1 in 591 | 1 in 2,326 | 1 in 1,645 | 1 in 1,465 | ||
| C00 | Lip | 0.6 | 0.2 | 0.6 | 0.4 | 0.3 | 0.5 | 0.4 |
| (0.5–0.7) | (0.1–0.3) | (0.5–0.7) | (0.3–0.5) | (0.25–0.35) | (0.4–0.6) | (0.37–0.43) | ||
| 1 in 1,240 | 1 in 4,302 | 1 in 1,332 | 1 in 2,296 | 1 in 2,999 | 1 in 1,907 | 1 in 1,991 | ||
| Female | ||||||||
| All | All site (H&N) | 9.4 | 6.2 | 6.8 | 10.1 | 8.4 | 7.3 | 8.0 |
| (8.9–9.9) | (5.7–6.7) | (6.5–7.1) | (9.7–10.5) | (8.2–8.6) | (7.1–7.5) | (7.9–8.1) | ||
| 1 in 92 | 1 in 141 | 1 in 128 | 1 in 83 | 1 in 101 | 1 in 118 | 1 in 107 | ||
| C03-C06 | Mouth | 4.8 | 2.6 | 2.3 | 3.6 | 4.0 | 3.4 | 3.5 |
| (4.4–5.2) | (2.3–2.9) | (2.1–2.5) | (3.4–3.8) | (3.8–4.2) | (3.3–3.5) | (3.4–3.6) | ||
| 1 in 174 | 1 in 340 | 1 in 384 | 1 in 234 | 1 in 204 | 1 in 254 | 1 in 244 | ||
| C01-C02 | Tongue | 2.7 | 1.9 | 2.3 | 1.6 | 2.1 | 2.2 | 2.1 |
| (2.4–3.0) | (1.6–2.2) | (2.1–2.5) | (1.5–1.7) | (2.0–2.2) | (2.1–2.3) | (2.0–2.2) | ||
| 1 in 334 | 1 in 430 | 1 in 381 | 1 in 501 | 1 in 390 | 1 in 398 | 1 in 403 | ||
| C12-C13 | Hypopharynx | 0.6 | 0.2 | 0.5 | 1.2 | 0.9 | 0.6 | 0.7 |
| (0.5–0.7) | (0.1–0.3) | (0.4–0.6) | (1.1–1.3) | (0.8–1.0) | (0.5–0.7) | (0.66–0.74) | ||
| 1 in 1,722 | 1 in 3,364 | 1 in 2,025 | 1 in 623 | 1 in 1,031 | 1 in 1,478 | 1 in 1,207 | ||
| C32 | Larynx | 0.6 | 0.6 | 0.7 | 1.0 | 0.4 | 0.5 | 0.6 |
| (0.5–0.7) | (0.5–0.7) | (0.6–0.8) | (0.9–1.1) | (0.3–0.5) | (0.4–0.6) | (0.57–0.63) | ||
| 1 in 1,326 | 1 in 1,782 | 1 in 1,157 | 1 in 820 | 1 in 2,202 | 1 in 1,805 | 1 in 1,455 | ||
| C11 | Nasopharynx | 0.1 | 0.2 | 0.2 | 1.1 | 0.3 | 0.1 | 0.3 |
| (0.05–0.15) | (0.1–0.3) | (0.1–0.3) | (1.0–1.2) | (0.26–0.34) | (0.07–0.13) | (0.28–0.32) | ||
| 1 in 9,394 | 1 in 4,530 | 1 in 3,632 | 1 in 852 | 1 in3,787 | 1 in 6,429 | 1 in 2,791 | ||
| C09 | Tonsil | 0.2 | 0.2 | 0.3 | 0.6 | 0.2 | 0.1 | 0.2 |
| (0.1–0.3) | (0.1–0.3) | (0.2–0.4) | (0.5–0.7) | (0.17–0.23) | (0.07–0.13) | (0.18–0.22) | ||
| 1 in 5,827 | 1 in 3,142 | 1 in 3,092 | 1 in 1,401 | 1 in 5,387 | 1 in 5,861 | 1 in 3,491 | ||
| C10 | Other oropharynx | 0.1 | 0.1 | 0.2 | 0.3 | 0.2 | 0.1 | 0.2 |
| (0.05–0.15) | (0.04–0.16) | (0.1–0.3) | (0.2–0.4) | (0.16–0.24) | (0.07–0.13) | (0.18–0.22) | ||
| 1 in 10,124 | 1 in 8,048 | 1 in 3,700 | 1 in 2,587 | 1 in 4,333 | 1 in 6,359 | 1 in 4,522 | ||
| C00 | Lip | 0.3 | 0.1 | 0.1 | 0.3 | 0.2 | 0.2 | 0.2 |
| (0.2–0.4) | (0.03–0.17) | (0.06–0.14) | (0.2–0.4) | (0.17–0.23) | (0.17–0.23) | (0.18–0.22) | ||
| 1 in 3,091 | 1 in 6,591 | 1 in 6,203 | 1 in 2,512 | 1 in 5,847 | 1 in 5,268 | 1 in 4,612 | ||
| C14 | Pharynx unspecified | 0.1 | 0.1 | 0.1 | 0.3 | 0.2 | 0.1 | 0.2 |
| (0.04–0.16) | (0.03–0.17) | (0.06–0.14) | (0.2–0.4) | (0.16–0.24) | (0.07–0.13) | (0.18–0.22) | ||
| 1 in 9,951 | 1 in 6,409 | 1 in 5,637 | 1 in 3,430 | 1 in 4,975 | 1 in 7,284 | 1 in 5,516 | ||
ASIR: Age-standardised incidence rate per 100,000 population, 95% CI (in parenthesis) and cumulative risk (0–74 age group)