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. 2023 Sep 27;2023:8887981. doi: 10.1155/2023/8887981

Table 2.

Type of SCD and baseline biological parameters in sickle cell children with and without cholelithiasis and their relationship to cholelithiasis at the National Reference Center for Sickle Cell Disease.

Characteristics Cholelithiasis Without cholelithiasis OR IC 95% P
n (%) n (%)
Type of SCD
 S/β thalassemia 6 16.22 21 28.38 0.57 0.25–1.29 0.16
 SS 31 83.78 53 71.62 1.17 0.96–1.43
 SC 0 0
Hb (g/dL)
 <6 13 35.14 14 18.92 1.82 0.69–4.74 0.21
 ≥6 24 64.86 60 81.08 0.8 0.54–1.15
MCV∗∗ (FL)
 <100 24 64.86 44 59.46 0.86 0.80–1.47 0.58
 ≥100 13 35.14 30 40.54 1.09 0.44–1.62
MCHC∗∗∗ (g/dL)
 <32 19 51.35 23 31.08 1.26 0.63–2.52 0.81
 ≥32 18 48.65 51 68.92 0.85 0.53–1.38
WBC∗∗∗∗ (/mm3)
 <12000 21 56.76 44 59.46 0.67 0.39–1.13 0.11
 ≥12000 16 43.24 30 40.54 1.7 0.85–3.38
Platelets (giga/L)
 150–450 31 83.78 56 75.68 1.28 0.89–1.82 0.17
 ≥450 6 16.22 18 24.32 0.51 0.18–1.41

Sickle beta-zero-thalassemia (5 cases vs 8 controls) and sickle beta-plus-thalassemia (1 case vs 13 controls). ∗∗Mean corpuscular volume. ∗∗∗Mean corpuscular Hb concentration. ∗∗∗∗White blood cells.