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. 2023 Oct 4;14:6182. doi: 10.1038/s41467-023-41937-9

Table 1.

Lifetime burden of tuberculosis stratified by RS-TB and RR-TB, globally and per incident tuberculosis case, 2020

Form of disease Outcome TB disease Post-TB Total
Total global DALYs (millions)
RS-TB YLLs 63.5 (55.5, 72.1) 39.7 (25.6, 57.9) 103.2 (86.4, 122.2)
YLDs 4.9 (2.5, 8.3) 14.5 (8.3, 23.5) 19.4 (12.4, 28.5)
DALYs 68.4 (59.7, 77.6) 54.2 (35.6, 79.7) 122.6 (100.8, 149.0)
RR-TB YLLs 3.6 (3.1, 4.3) 2.2 (1.3, 3.2) 5.9 (4.8, 7.1)
YLDs 0.2 (0.1, 0.3) 0.9 (0.4, 1.4) 1.1 (0.6, 1.6)
DALYs 3.8 (3.2, 4.4) 3.1 (1.8, 4.4) 6.9 (5.5, 8.5)
All disease YLLs 67.1 (58.8, 76.1) 42.0 (27.6, 60.7) 109.1 (91.9, 128.9)
YLDs 5.1 (2.6, 8.6) 15.3 (8.8, 24.7) 20.4 (13.1, 29.9)
DALYs 72.2 (63.2, 81.9) 57.3 (37.7, 83.5) 129.5 (107.1, 156.9)
DALYs per incident tuberculosis case
RS-TB YLLs 6.7 (5.9, 7.5) 4.2 (2.8, 6.0) 10.9 (9.3, 12.7)
YLDs 0.5 (0.3, 0.9) 1.5 (0.9, 2.5) 2.0 (1.3, 3.0)
DALYs 7.2 (6.4, 8.0) 5.7 (3.7, 8.4) 12.9 (10.8, 15.6)
RR-TB YLLs 9.1 (7.6, 10.5) 5.6 (3.3, 7.8) 14.6 (12.0, 17.1)
YLDs 0.5 (0.2, 0.8) 2.1 (1.1, 3.3) 2.6 (1.6, 3.9)
DALYs 9.6 (8.1, 11.0) 7.7 (4.5, 10.7) 17.3 (13.8, 20.6)
All disease YLLs 6.8 (6.0, 7.6) 4.2 (2.8, 6.1) 11.0 (9.4, 12.8)
YLDs 0.5 (0.3, 0.9) 1.5 (0.9, 2.5) 2.1 (1.3, 3.0)
DALYs 7.3 (6.5, 8.1) 5.8 (3.8, 8.4) 13.1 (11.0, 15.7)

YLLs ‘years of life lost’ due to fatal disease consequences, YLDs ‘years lived with disability’ due to non-fatal disease consequences, DALYs disability-adjusted life years (the sum of YLLs and YLDs), RR-TB rifampicin-resistant tuberculosis, RS-TB rifampicin-susceptible tuberculosis.

Values in parentheses represent 95% uncertainty intervals.