Table 2.
Efficacy of T2D preventive interventions according to sociodemographic effect modifiers.
| T2D preventive strategies | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Lifestyle intervention | Dietary pattern intervention | Dietary supplements intervention | |||||||
| Modifier | Number of studies | Effect modificationa | Certainty of evidenceb | Number of studies | Effect modificationa | Certainty of evidenceb | Number of studies | Effect modificationa | Certainty of evidenceb |
| Age | 12 |
Yes: 7 studies No: 5 studies |
Grade D | 3 | No: 3 studies | Grade D | 4 |
Yes: 1 study No: 3 studies |
Grade D |
| Sex | 16 |
Yes: 1 study No: 15 studies |
Grade D | 2 | No: 2 studies | Grade D | 1 | Yes: 1 study | Grade D |
| Race/ethnicity | 3 | No: 3 studies | Grade D | 1 | No: 1 study | Grade D | 1 | No: 1 study | Grade D |
| Socioeconomic status/ Education | 4 |
Yes: 1 study No: 3 studies |
Grade D | – | – | – | – | – | – |
| Location | 2 | No: 2 studies | Grade D | – | – | – | 1 | No: 1 study | – |
Overview of the included studies investigating whether sociodemographic factors modify the response to T2D preventive intervention strategies.
aYes/No corresponds to significant/nonsignificant effect modification, as reported in the study.
bCertainty of evidence denotes consistency, Grading based on Diabetes Canada scale A to D.