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. 2023 Sep 21;14:1243598. doi: 10.3389/fpsyg.2023.1243598

Table 1.

Summary of articles related to gratitude studies.

First author (year) Study design Type participant N Mean Age (SD) % Male Gratitude measure(s) Intervention Time frame Summary of findings
Redwine et al. (2016) Randomized blinded trial Patients with stage B heart failure 70 66(7.58) 95% GQ6 Gratitude journal 8 weeks Gratitude was associated with lower levels of inflammatory biomarkers, such as CRP, TNF-α, IL-6 and sTNFr1, and higher parasympathetic heart rate variability.
Moieni et al. (2019) Randomized blinded trial Healthy middle-aged women 76 43(4.70) 0% GQ6 Writing aimed at inducing gratitude 6 weeks Gratitude interventions had no direct effect on inflammatory markers. Gratitude interventions were correlated with a decreased percentage of monocytes producing proinflammatory IL-6 and TNF- α through the habit of increased support-giving.
Schache et al. (2020) Randomized blinded trial Type 1 diabetes patients 80 NR NR GQ6 Gratitude journal 8 weeks Gratitude interventions can help improve glucose control in patients with type 1 diabetes.
Wolfe and Patterson (2017) Randomized blinded trial Undergraduates 140 20 (6.93) 0% Gratitude listing 2 weeks Gratitude interventions were demonstrated to effectively reduce eating disorders, lower the risk of depressive symptoms and reduce negative psychological outcomes.
Fritz et al. (2019) Randomized blinded trial Undergraduates (1) and high school students (2) 327(1) 1017(2) (1):19(1.30) (2):NR 24%(1) NR (2) GQ6 Gratitude letter (1):2 weeks (2):4 weeks Gratitude interventions can improve eating behaviors.
Sultan et al. (2018) Randomized blinded trial Patients with CHD 40 48.64 100% GQ6 An intervention that focuses on enhancing positive psychological attributes 8 weeks Higher levels of gratitude and lower CHD symptoms were observed in the positive psychological intervention group. Positive psychology interventions can facilitate gratitude and help reduce the risk of CHD.
Jackowska et al. (2016) Randomized blinded trial Young women 119 26 0% Gratitude journal 2 weeks Gratitude interventions are associated with a decrease in diastolic blood pressure and improvements in depression and sleep quality when compared with the control.
Digdon and Koble, (2011) Randomized blinded trial Undergraduates 41 23 (6.11) 22% Positive events journaling 1 week Improvements in sleep quality and quantity and reductions in the level of pre-sleep arousal were observed after the gratitude intervention.
O’Connell et al. (2017) Randomized blinded trial Mainly young adult sample 192 27(12.60) 33% GQ6 Reflective behavior – reflective only – control journaling 3 times a week for 3 weeks Gratitude interventions had great potential in decreasing negative feelings and reducing their adverse effects on health.
Salces-Cubero et al. (2019) Randomized blinded trial Elderly 124 69(7.78) 40% Positive activities available to train gratitude One week before intervention, 1 week after intervention, and a month after intervention completion Gratitude interventions were associated with decreases in negative mental states and increases in positive psychological states, which can enhance patients’ subjective well-being and life satisfaction.
Yang et al. (2018) Randomized blinded trial Prisoners 144 NR NR Gratitude journal and group seminars 6 weeks Gratitude interventions can decrease negative mental states and significantly enhance the subjective well-being of prisoners.
Cheng et al. (2015) Randomized blinded trial Medical workers 102 NR 35% Gratitude journal Twice a week for 4 weeks Gratitude interventions were correlated with decreased self-reported depression symptoms and perceived stress.
Ramírez et al. (2014) Randomized blinded trial Elderly 46 71 (7.06) 65% Gratitude letter Once a week for 9 weeks Gratitude interventions can significantly reduce depressive symptoms and anxiety and enhance subjective well-being and life satisfaction.
Watkins et al. (2015) Randomized blinded trial College students 129 NR 29% SGRAT Gratitude journal 6 weeks Gratitude interventions can reduce depressive symptoms and enhance subjective happiness over the course of 5 weeks after the intervention.
Southwell and Gould, (2017) Randomized blinded trial Persons with depression or anxiety disorders 109 34(10.80) 12% GQ6 Gratitude journal 3 weeks Participants with a high level of gratitude have lower scores on sleep difficulties, anxiety and depression.
Hazlett et al. (2021) Randomized blinded trial Healthy women 61 43(4.80) 0% Writing aimed at inducing gratitude Once a week for 6 weeks Gratitude interventions may decrease sympathetic nervous system activity by reducing amygdala reactivity and activating the ventral striatum and diaphragm area.
Kyeong et al. (2017) Randomized blinded trial Healthy people 32 23 (2.50) 47% Gratitude and resentment interventions 5 min The average heart rate during the gratitude intervention was lower than the average heart rate during the resentment intervention
Rash et al. (2011) Randomized blinded trial Adult sample 56 23 (3.00) 54% GQ6 Gratitude contemplation Twice a week for 4 weeks Gratitude practices can reduce stress, increase cardiac coherence and result in more ordered ECG waveforms and greater physiological coordination.
Matvienko-Sikar and Dockray, (2017) Randomized blinded trial Pregnant women 46 34(3.04) 0% GDP Gratitude journal Four times a week for 3 weeks The gratitude intervention group showed lower cortisol and stress levels in wakefulness and sleep during pregnancy compared to the control group that received conventional therapy.

ACS, acute coronary syndrome; CHD, coronary heart disease; ET-1, endothelin-1; GDP, the Gratitude during Pregnancy Scale; GQ6, gratitude questionnaire 6; GRAT, gratitude, resentment, and appreciation test; NR, not reported; SGRAT, short gratitude, resentment, and appreciation test; sICAM-1, soluble intercellular adhesion molecule-1.