TABLE 1.
Slopes of the regressions of IE on the predictors and the correlation coefficients
Antibiotic and regimen | AUC/MIC
|
AUCeff
|
Teff
|
|||
---|---|---|---|---|---|---|
Slope [log (CFU/ ml) · h] | r2 | Slope [log (CFU/ ml) · h] | r2 | Slope (log CFU/ml) | r2 | |
Trovafloxacin q.d. | 276a | 0.97 | 250a | 0.96 | 9.0 | 0.96 |
Ciprofloxacin q.d. | 151b | 0.95 | 141b | 0.93 | 9.7 | 0.94 |
Ciprofloxacin b.i.d. | 113 | 0.98 | 108 | 0.96 | 8.6 | 0.98 |
Statistically significant difference between the drugs.
Statistically significant difference between the regimens of ciprofloxacin.