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. 2023 Sep 27;2023:5548112. doi: 10.1155/2023/5548112

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Copyright © 2023 Xin Tang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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ADSC-Exos antagonizes the inhibitory effect of DHT on hair follicle growth. (a) CCK-8 absorbance values of ADSC-Exos and/or DHT treated DPCs after 72 hr. (b) Scratch experiment of ADSC-Exos and/or DHT treated DPCs for 0, 12, 24, and 48 hr, scale bar: 100 μm. (c) Quantitative analysis of scratch area in (d) Hair follicle growth graph, n = 6. (e) Mean length of hair shaft increase (mm), n = 6. (f) Morphology of hair follicle growth at 0, 2, 4, 6, 8, and 10 days after ADSC-Exos and/or DHT treatment, scale bar: 500 μm. (g) Ki67 expression of hair follicles in each group, scale bar: 100 μm. (h) The proportion of Ki67+ hair matrix keratinocytes in each group. ^∗/#P < 0.05, ^∗∗/##P < 0.01, ^{∗∗∗/###}P < 0.001. Comparison with ^∗control group and ^#DHT group.