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. 2023 Sep 21;14:1258997. doi: 10.3389/fmicb.2023.1258997

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Copyright © 2023 Overton, Manuel, Lawrence and Snyder.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Initial viral attachment to pili. (A) Subtomographic average of STIV virions and pili show pilus recognition is mediated by interactions with the 2nd (light purple) and 3rd (dark purple) jelly roll domains of the C381 turret protein. To the right, an enlarged view of a single turret/pilus interaction. (B) Strictly conserved, surface exposed residues lie within these regions and potentially mediate recognition. These include Asn196 and Ser215 in domain 2, and Glu285 and Asn289 in domain 3. Adapted from Hartman et al. (2019).