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. 2023 Oct 5;10(4):045002. doi: 10.1117/1.NPh.10.4.045002

Table 1.

Results of two-way repeated-measures ANOVA for hemodynamic responses and oxygenation changes in the relatively deeper layer over the forehead in response to hypoxia.

Items Variables Results of two-way repeated measures ANOVA
df F P Pη2
Deoxy-Hb
Ch 1.00 10.10 0.007** 0.42
Error
14.00



Time 2.80 230.52 0.000*** 0.94
Error
39.26



Ch* time 1.50 6.98 0.008** 0.33
Error
20.97



Oxy-Hb
Ch 1.00 17.62 0.001** 0.56
Error
14.00



Time 3.65 61.14 0.000*** 0.81
Error
51.08



Ch* time 3.01 8.50 0.000*** 0.38
Error
42.14



Total-Hb
Ch 1.00 1.16 0.299 0.08
Error
14.00



Time 3.99 30.75 0.000*** 0.69
Error
55.91



Ch* time 2.81 1.93 0.144 0.12
Error
39.30



StO2 Ch 1.00 17.62 0.001** 0.56
Error
14.00



Time 3.65 61.14 0.000*** 0.81
Error
51.08



Ch* time 3.01 8.50 0.000*** 0.38
Error 42.14

The effects of hypoxia on changes in hemodynamics in the relatively deep layer over the forehead (time) and the difference in hemodynamic responses between FPL and FPR (channel; Ch) were analyzed using two-way repeated-measures ANOVA (Ch × time) in conjunction with the Bonferroni post hoc test for multiple comparisons. Asterisks indicate significant main effects of time or Ch or interaction at *P<0.05, **P<0.01, and ***P<0.001.

Oxy-Hb, oxygenated hemoglobin; deoxy-Hb, deoxygenated hemoglobin; total-Hb, total hemoglobin; StO2, tissue oxygen saturation; FPL, left frontal pole; FPR, right frontal pole; ANOVA, analysis of variance.