Fig. 3.

Comparing sulfur usage in orthologous protein pairs.A, to avoid potentially confounding effects of evolutionary changes in protein function, only equivalent and alignable protein domains within strict 1-to-1 orthologs are considered. B, relations between protein abundance and the sulfur-usage ratio yeast/human. Each data point corresponds to one orthologous pair of proteins; the abundance values on the x-axis are taken from the yeast protein. Violin plots indicate median and percentiles 25 and 75, for six equally sized bins. A linear regression was fit for the regression line. Spearman’s ρ and its p-value were separately derived.