Table I.

Regulators of FLOT1.

First author/s, year	Regulation	Regulator	Mode of regulation	(Refs.)
Liu et al, 2019	Translational regulation	HOTAIR	The upregulation of HOTAUR promotes the expression of FLOT1 in HCC.	(42)
Cai et al, 2021		A1BG-AS1	The upregulation of A1BG-AS1 promotes the expression of FLOT1 in BC.	(44)
Lv et al, 2020		TUG1	The upregulation of TUG1 promotes the expression of FLOT1 in ccRCC.	(45)
Wang et al, 2022		FAM201A	The upregulation of FAM201A promotes the expression of FLOT1 in CC.	(59)
Li et al, 2021		SNHG6	The upregulation of SNHG6 promotes the expression of FLOT1 in Malignant glioma.	(60)
Liu et al, 2019,		miR-214-3p,	The upregulation of miR-214-3p and miR-6809-5p	(42,61)
Yang et al, 2019		miR-6809-5p	inhibits the expression of FLOT1 in HCC.
Li et al, 2013,		miR-485-5p,	The upregulation of miR-485-5p and miR-124	(44,62)
Cai et al, 2021		miR-124	inhibits the expression of FLOT1 in BC.
Yang et al, 2015,		miR-31-5p,	The upregulation of miR-31-5p, miR-506 and	(45,56)
Lv et al, 2020		miR-506, miR-124-3p	miR-124-3p inhibits the expression of FLOT1 in ccRCC.
Kan et al, 2020,		miR-1271-5p,	The upregulation of miR-1271-5p and miR-1294	(43,59)
Wang et al, 2022		miR-1294	inhibits the expression of FLOT1 in CC.
Gong et al, 2013		miR-138	The upregulation of miR-138 inhibits the expression of FLOT1 in ESCC.	(63)
Jang et al, 2019	Post-	UBC9	UBC9 sumolylates FLOT1 at Lys15 and Lys195.	(5)
Cremona et al, 2011	translational modification	PKC	PKC phosphorylates FLOT1 at Ser315	(15)
Riento et al, 2009		Fyn	Fyn phosphorylates FLOT1 in Tyr160.	(12)