Table 1. In Vitro Cytotoxicity Evaluation of Saponins 3a–c.

compound	IC50 (μM)a
	A549	DLD-1	WS1
2	3.3 ± 0.3	2.5 ± 0.2	9 ± 1
3a	4.2 ± 0.4	5.4 ± 0.6	22 ± 2
3b	10 ± 1	10 ± 2	41 ± 5
3c	2.5 ± 0.2	4.3 ± 0.5	21 ± 1
etoposideb	4.1 ± 0.5	1.3 ± 0.1	5 ± 1

^aIC₅₀ values ± SD (n = 3) are representative of two different experiments.

^bUsed as a positive control. A549: human lung adenocarcinoma cells; DLD-1: human colon cancer cells; WS-1: human skin fibroblast.