Table 1.
Autoimmune Disease datasets used in this study.
| Autoimmune Disorder | Abbreviation | Cases | Controls | SNPs in sumstats | SNPs in PRS | SNPs in PRS (no HLA) | PMID |
|---|---|---|---|---|---|---|---|
| Rheumatoid Arthritis | RA | 14,361 | 43,923 | 8,747,962 | 309 | 132 | 24390342 |
| Systemic Lupus Erythematosus | SLE | 4,036 | 6,959 | 7,915,251 | 200 | 144 | 26502338 |
| Vitiligo Late Onset | VITL | 1,467 | 19,156 | 7,552,975 | 77 | 49 | 30674883 |
| Vitiligo Early Onset | VITE | 704 | 9,031 | 8,020,475 | 84 | 60 | 30674883 |
| Type 1 Diabetes | T1D | 9,358 | 15,705 | 6,621,966 | 236 | 198 | 32005708 |
| Primary Sclerosing Cholangitis | PSC | 2,871 | 12,019 | 7,891,602 | 157 | 50 | 27992413 |
| Psoriasis | PSO | 2,997 | 9,183 | 161,173 | 191 | 121 | 23143594 |
| Multiple Sclerosis | MS | 9,772 | 17,376 | 472,086 | 147 | 86 | 21833088 |
| Celiac Disease* | CEL | 12,041 | 12,228 | 139,553 | 122 | 100 | 22057235 |
| Juvenile Idiopathic Arthritis | JIA | 2,816 | 13,056 | 122,330 | 45 | 5 | 23603761 |
| Myasthenia Gravis** | MG | 1,401 | 3,508 | 5,755,778 | 21 | 14 | 34400559 |
*We included the summary statistics only from the European ancestry individuals in this study.
**For the PRS calculations we used the summary statistics after excluding the UK Biobank samples, while for the rest of the analyses we included the full dataset described in the study.
The number of SNPs in the PRS calculations corresponds to the independent SNPs with p<10-5.