Fig. 6.

Treg-Exos promote BSCB repair in vivo by delivering miR-2861. A, B Co-immunostaining and quantification of TJs protein and blood vessels at the injured site in the spinal cord on day 7 after spinal cord injury (n = 3). C Western blotting was used to detect the expression of the TJs protein of the spinal cord in miR-NC^KD-Exos, miR-2861^KD-Exos, miR-NC^OE-Exos, and miR-2861^OE-Exos-treated mice. D–G MEP analysis (n = 3) and BMS score (n = 6) were used to evaluate the recovery of motor ability at day 28 after the intervention of miR-NC^KD-Exos, miR-2861^KD-Exos, miR-NC^OE-Exos, and miR-2861^OE-Exos in mice with spinal cord injury