Table 4.

Comparison of the genotypic distribution of the P. vivax-malaria and control group (CG)

Genotype	Pva (%)	CGb (%)	P-valuec	OR (95% CI)d	OR (95% CI)e
FAS (rs10562972)
DEL/DEL	1 (3.8)	1 (0.9)	0.996	1.000 (0.000-∞)	1.051 (0.000-∞)
INS/DEL	1 (3.8)	24 (23.7)
INS/INS	24 (92.4)	76 (75.4)	0.143	2.267 (0.455–5.109)	1.801 (0.860–4.259)
FADD (rs4197)
DEL/DEL	10 (38.5)	45 (44.6)	0.457	0.855 (0.492–1.473)	0.802 (0.446–1.426)
INS/DEL	13 (50.0)	48 (47.5)
INS/INS	3 (11.5)	8 (7.9)	0.365	1.169 (0.679–2.032)	1.420 (0.636–3.020)
CASP8 (rs3834129)
DEL/DEL	5 (19.2)	19 (18.8)	0.818	1.015 (0.534–1.675)	0.923 (0.458–1.780)
INS/DEL	14 (53.9)	43 (42.6)
INS/INS	7 (26.9)	39 (38.6)	0.099	0.985 (0.536–1.870)	0.594 (0.312–1.095)
CASP8 (rs59308963)
DEL/DEL	7 (26.9)	29 (28.7)	0.805	0.947 (0.526–1.670)	0.925 (0.492–1.699)
INS/DEL	16 (61.6)	53 (52.5)
INS/INS	3 (11.5)	19 (18.8)	0.142	1.055 (0.597–1.901)	0.551 (0.229–1.165)
CASP9 (rs61079693)
DEL/DEL	5 (19.2)	33 (32.7)	0.311	0.657 (0.349–1.189)	0.720 (0.375–1.338)
INS/DEL	18 (69.3)	44 (43.6)
INS/INS	3 (11.5)	24 (23.7)	0.329	1.522 (0.841–2.860)	0.701 (0.330–1.390)
CASP3 (rs4647655)
DEL/DEL	17 (65.4)	51 (50.5)	0.176	1.466 (0.848–2.571)	1.499 (0.840–2.710)
INS/DEL	7 (26.9)	40 (39.6)
INS/INS	2 (7.7)	10 (9.9)	0.702	0.682 (0.389–1.178)	0.853 (0.360–1.822)
BCL2 (rs11269260)
DEL/DEL	8 (30.8)	19 (18.8)	0.167	1.466 (0.813–2.597)	1.532 (0.828–2.800)
INS/DEL	11 (42.3)	45 (44.6)
INS/INS	7 (26.9)	37 (36.6)	0.233	0.682 (0.385–1.230)	0.688 (0.368–1.254)
TP53 (rs17880560)
DEL/DEL	20 (77.0)	63 (62.4)	0.271	1.524 (0.856–2.786)	1.409 (0.773–2.634)
INS/DEL	5 (19.2)	34 (33.7)
INS/INS	1 (3.8)	4 (3.9)	0.909	0.656 (0.359–1.167)	1.063 (0.324–2.768)

Pv^a, Plasmodium vivax; CG^b, Control group; P-value^c obtained through logistic regression adjusted by sex; Crude Odds Ratio (OR)^d; Adjusted OR^e