Connected Health Innovation Research Program (C.H.I.R.P.) Foundational Design. A suite of software and device technologies accessible to the cardio-oncology population has been established. We have formed an interdisciplinary research team and established an academia-industry collaborative foundation for retrospective, prospective, and case research studies in digital and connected health. Thus, we have successfully launched C.H.I.R.P.. In addition, a beta version of our website is currently available, and we are developing a mobile application to centralize digital health patient technologies. We plan to incorporate remote patient monitoring and wearable physiological pattern information into patient charts, through an existing cardiology focused virtual care platform in collaboration with C.H.I.R.P. We hope to incorporate innovative solutions for patients like “Genius Bars” to enhance orientation to these new digital health technologies. C.H.I.R.P. team members have benefited from real world experience interacting and forming relationships with digital health companies. The development of our connected health cadre of industry partners has been accomplished by first screening companies for technologies that fit with our goals and have the potential to improve outcomes in cardio-oncology patients. This has led to the screening of ~30 companies through the American Medical Association innovation network and LinkedIn, with subsequent recruitment of ~20, and collaboration with ~10 companies. We have especially been investigating the technologies of 3 companies that specifically cater their technology or software to cardio-oncology patients, and are conducting initial retrospective, prospective, and case studies with these companies. Additionally, we collaborate with seven companies that offer their technology or software to a general user population; we are currently conducting retrospective analyses on the general users of these technologies or software.