Non-noxious (Mechanical)/Noxious (thermal/Electrical) stimulus |
186
|
Healthy adults |
Young (22) old (62) |
Older adults exhibit higher ratings of the intensity and unpleasantness of thermal pain and enhanced temporal summation of thermal pain relative to younger adults |
187
|
Healthy adults |
Young (22) old (62.2) |
Older adults have lower ischemic pain thresholds and tolerances assessed via the modified submaximal effort tourniquet procedure |
183
|
Healthy adults |
Young (30) old (78.9) |
The study finds an age-dependent temporal relationship with pain stimuli. There is a higher thermal and electrical stimulation threshold when the stimulus duration is short, but no differences when the stimulus duration is long |
184
|
Healthy adults |
Young (27) old (71) |
There are stimulus-specific age differences. Non-noxious stimuli thresholds increase with age whereas pressure pain thresholds decrease. Heat pain thresholds show no age-related changes. Older adults demonstrate greater temporal summation, but pain summation was not affected |
181
|
Healthy adults |
Middle (45–56) older (57–79) |
There are stimulus-specific age differences. Older adults are less sensitive to warm and painful heat stimuli than middle-aged adults. In addition, there is a greater decrease in sensitivity associated with aging in the lower extremities |
103
|
Healthy adults |
Young (21.4) older (68.1) |
Observed greater elevations in pro-inflammatory cytokines (TNF-α and IL-8) following cold pressor task and focal heat pain in older subjects. Only greater elevations of IL-6 after cold pressor task in older subjects Anti-inflammatory cytokines (IL-4, IL-5, and IL-10) peaked later in older subjects with increased elevations for focal heat pain only |
182
|
Healthy adults |
Young (27) old (69) |
Heat pain threshold increases with age, however, adult adults report more pain intensity. Inhibitory controls were identical between old and young adults following placebo analgesia |
185
|
Healthy adults |
Young (34) old (67) |
Older adults experienced greater temporal summation of spatial perception of cold stimuli compared with younger adults. Temporal summation of pain intensity for heat or cold stimuli showed no age differences |
Conditioned pain modulation |
178
|
Healthy adults |
Young (23) old (78) |
Older adults needed a higher intensity of noxious stimulation to first report pain |
175
|
Healthy adults |
Young (21) old (63) |
Older adults did not exhibit inhibitory controls whereas younger adults were able to on repetitive stimulus |
176
|
Healthy adults |
Young (25) elderly (47) old (68) |
Endogenous pain modulation was negatively correlated with advancing age |
177
|
Healthy adults |
Young (25) old (65.2) |
Older adults exhibit decreased inhibitory controls compared to young adults |
179
|
Healthy adults |
Young (29) old (63) |
Older adults have an age-related reduction in inhibitory processes |
180
|
Healthy adults |
Young (24) old (64) |
Older individuals experienced greater fluctuations in pain sensitivity following the varying intensity of the conditioned stimulus |
Exercise |
190
|
Healthy adults |
Young (22) old (64) |
There are age-related differences in exercise-induced hypoalgesia. Younger adults experience greater hypoalgesia following exercise compared with older adults |