Table 3. ANOVA Results for the Coefficient of the Cubic Model for the Zone of Inhibition.
| source | sum of squares | df | mean square | F-value | P value | |
|---|---|---|---|---|---|---|
| model | 1139.61 | 20 | 56.98 | 12.46 | <0.0001 | significant |
| A-yeast extract | 1.56 | 1 | 1.56 | 0.3417 | 0.5641 | |
| B-malt extract | 14.06 | 1 | 14.06 | 3.08 | 0.0917 | |
| C-dextrose | 20.25 | 1 | 20.25 | 4.43 | 0.0456 | |
| D-pH | 0.0156 | 1 | 0.0156 | 0.0034 | 0.9538 | |
| E-temperature | 2.64 | 1 | 2.64 | 0.5776 | 0.4544 | |
| AB | 4 | 1 | 4 | 0.8749 | 0.3586 | |
| AC | 1 | 1 | 1 | 0.2187 | 0.6441 | |
| AD | 1 | 1 | 1 | 0.2187 | 0.6441 | |
| AE | 12.25 | 1 | 12.25 | 2.68 | 0.1142 | |
| BC | 0.25 | 1 | 0.25 | 0.0547 | 0.817 | |
| BD | 5.06 | 1 | 5.06 | 1.11 | 0.3027 | |
| BE | 0.0625 | 1 | 0.0625 | 0.0137 | 0.9079 | |
| CD | 16 | 1 | 16 | 3.5 | 0.0731 | |
| CE | 12.25 | 1 | 12.25 | 2.68 | 0.1142 | |
| DE | 0.25 | 1 | 0.25 | 0.0547 | 0.817 | |
| A2 | 128.24 | 1 | 128.24 | 28.05 | <0.0001 | |
| B2 | 117.33 | 1 | 117.33 | 25.66 | <0.0001 | |
| C2 | 101.88 | 1 | 101.88 | 22.28 | <0.0001 | |
| D2 | 880.02 | 1 | 880.02 | 192.48 | <0.0001 | |
| E2 | 422.56 | 1 | 422.56 | 92.42 | <0.0001 | |
| residual | 114.3 | 25 | 4.57 | |||
| lack of fit | 101.47 | 20 | 5.07 | 1.98 | 0.2316 | not significant |
| pure error | 12.83 | 5 | 2.57 | |||
| cor total | 1253.91 | 45 |