Table 1. Clinical and Demographic Characteristics of Alzheimer’s Dementia Patients, Patients with Amnestic Mild Cognitive Impairment, and Healthy Subjectsa.
| parameter | AD patients (n = 40) | aMCI patients (n = 40) | controls (n = 10) |
|---|---|---|---|
| age (years ± SD) | 71 ± 9 | 70 ± 7 | 61 ± 12 |
| male/female ratio (%) | 12/28 (30%) | 17/23 (42%) | 2/8 (20%) |
| years of education | 13.5 ± 2.9 | 14.8 ± 3.1 | 17 ± 1.65 |
| Mini-Mental score | 19 ± 4 | 25 ± 3 | 29.9 ± 0 |
| PAI-1 (ng/mL) | 6.1 ± 0.9 | 4.7 ± 1.5 | 3.9 ± 0.8 |
| BDNF (ng/mL) | 15.7 ± 3.9 | 18.2 ± 3.0 | 15.8 ± 3.0 |
| PAI-1/BDNF ratio | 0.41 ± 0.12 | 0.26 ± 0.08 | 0.24 ± 0.04 |
a
SD: standard deviation; AD = Alzheimer’s disease; aMCI = amnestic mild cognitive impairment.