Skip to main content
. 2023 Sep 21;13:1239574. doi: 10.3389/fonc.2023.1239574

Table 3.

Continuous characteristics of all groups and univariate analysis.

PRP NPR P-value*
Complete resected by VAB Minimal residual disease on surgical pathology Total Gross residual disease Upgrade Total
Number of patients 29 (25%) 18 (15.5%) 47 (40.5%) 64 (55.2%) 5 (4.3%) 69 (59.5%)
Final diagnosis:
 IC
 IC+ DCIS
 DCIS
 DCIS with microinvasion
12
9
8
0
15
2
1
12 (25.5%)
24 (51.1%)
10 (21.3%)
1 (2.1%)
6
24
28
6
0
4
0
1
6 (8.7%)
28 (40.6%)
28 (40.6%)
7 (10.1%)
< 0.001
Age
Mean ± SD
(range)
59.31 ± 12.99 (31–91) 59.22 ± 13.39 (33–79) 59.27 ± 12.9 (31–91) 52.80 ± 11.32 (20–76) 58.40 ± 8.79 (44–66) 53.20 ± 11.19 (20–76) 0.008
Tumor size on image (mm), Mean ± SD (range) 8.03 ± 4.02 (4–25) 9.28 ± 3.29 (5–18) 8.50 ± 3.77 (4–25) 15.49 ± 14.47 (4–88) 9.33 ± 4.04 (7–14) 15.00 ± 14.00 (4–88) 0.008
Final tumor invasive size** (mm)
Mean ± SD (range)
4.99 ± 2.17 (2–11) 5.31 ± 2.04 (1–8) 5.11 ± 2.10 (1–11) 12.10 ± 9.93 (1–25) 4.76 ± 4.48 (0.8–12) 10.66 ± 7.10 (0.80–25) <0.001
Final tumor in situ size** (mm)
Mean ± SD (range)
3.88 ± 1.25 (2–6) 2.25 ± 0.35 (2–2.5) 3.55 ± 1.30 (2–6) 15.96 ± 11.98 (5–65) 15.96 ± 11.98 (5–65) <0.001
Ki67 (%) 13.50 ± 14.99 (2–80) 21.56 ± 21.17 (3–80) 16.65 ± 17.88 (2–80) 25.80 ± 19.29 (2–90) 18.00 ± 21.68 (5–55) 25.46 ± 19.21 (2–90) 0.016

*t-test.

**Final tumor size is referred as the largest pathological tumor size measured either on the VAB/EVAB or the surgical specimen, following the TNM stage system (17).