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. 2023 Sep 21;14:1228853. doi: 10.3389/fendo.2023.1228853

Table 2.

Comparisons of p-values from parametric ANOVA significance tests to nonparametric Kruskal-Wallis tests.

Variable ANOVA S vs O S vs N O vs N Kruskal-Wallis S vs O S vs N O vs N
Insulin <0.0001 <0.0001 0.69 <0.0001 <0.0001 <0.0001 0.10 <0.0001
HOMA-β 0.88 0.61 0.87 0.77 0.68 0.97 0.87 0.62
HOMA-IR <0.0001 <0.0001 0.61 <0.0001 <0.0001 <0.0001 0.020 <0.0001
Glucose <0.0001 <0.0001 0.085 <0.0001 <0.0001 <0.0001 0.038 <0.0001
HbA1c <0.0001 <0.0001 N/A N/A <0.0001 <0.0001 N/A N/A
TG 0.0015 0.004 0.68 0.002 <0.0001 0.003 0.42 <0.0001
LDL-C 0.003 0.71 0.002 0.003 0.0023 0.99 0.004 0.006
HDL-C 0.0007 0.0004 0.55 0.008 0.0005 0.0019 0.95 0.007
AST 0.33 0.33 N/A N/A 0.91 0.91 N/A N/A
ALT 0.054 0.054 N/A N/A 0.088 0.088 N/A N/A
FGF19 0.089 0.028 0.36 0.22 0.045 0.037 0.26 0.83
FGF21 0.36 0.65 0.16 0.27 0.10 0.84 0.10 0.18
FGF23 0.026 0.20 0.007 0.076 0.005 0.39 0.006 0.032
ANGPTL3 0.26 0.19 0.89 0.17 0.21 0.30 0.99 0.32
ANGPTL4 <0.0001 0.008 <0.0001 <0.0001 <0.0001 0.042 <0.0001 <0.0001
ANGPTL6 0.0004 0.061 0.039 <0.0001 0.0011 0.38 0.07 0.0007
Adipsin <0.0001 0.023 0.0016 <0.0001 <0.0001 0.18 0.0012 <0.0001
Adiponectin 0.007 0.0016 0.11 0.26 0.011 0.012 0.52 0.20
Myonectin 0.007 0.25 0.0019 0.020 0.0003 0.64 0.0002 0.004

S, Post-surgery group; O, Non-surgery comparator-subjects-with-obesity; N, group with normal-weight subjects; ANOVA, analysis of variance; BMI, body mass index; HbA1c, glycated hemoglobin; HOMA-β, homeostatic model assessment of beta cell function; HOMA-IR, homeostatic model assessment of insulin resistance; ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; TG, triglycerides; FGF, fibroblast growth factor; ANGPTL, angiopoietin-like protein. The three pairwise comparisons of the three groups are shown for both the parametric and non-parametric analyses.

N/A: the variable was not measured in the normal-weight group.