Figure 2.

HIV-1 DNA viral reservoir size over 192 weeks in HIV-1 patients receiving DTG monotherapy (n = 63) or cART (n = 29). P values are calculated with a linear mixed model, using a random intercept model with unique patients, to assess the overall time trend with DTG monotherapy as the reference. Triangles indicate values below limit of detection. Data up to week 48 previously reported as part of the EARLY-SIMPLFIED interim analysis [12]. Abbreviations: cART, combination antiretroviral therapy; DTG, dolutegravir; HIV-1, human immunodeficiency virus type 1.