Table 2:
Measurements of morphological features at baseline, and their change over time
| Baseline value | Coefficient of time (per year)† | P-value | |
|---|---|---|---|
| Max. major axis aortic diameter (mm) | 35.0 (33.0 – 38.5) | 3.19 (2.21 – 4.17) | < 0.001 |
| Max. minor axis aortic diameter (mm) | 32.0 (30.0 – 36.0) | 2.57 (1.67 – 3.47) | <0.001 |
| Size of intima tear axial (mm) | 7.0 (4.0 – 11.5) | 1.34 (0.89 – 1.87) | <0.001 |
| Size of intima tear sagittal (mm) | 5.0 (2.0 – 8.0) | 1.61 (1.11 – 2.11) | <0.001 |
| −0.08 (−0.13 – −0.04)‡ | <0.001 | ||
| Number of secondary tears (n)††† | 1.0 (0.0 – 1.0) | ||
| Circumferential extent of TL (°) | 103.0 (91.0 – 125.5) | −2.19 (−3.60 – −0.78) | 0.003 |
| Circumferential extent of FL (°) | 257.0 (234.5 – 269.0) | 2.19 (0.78 – 3.60) | 0.003 |
| Area TL (cm2) | 2.5 (2.0 – 3.3) | 0.32 (0.20 – 0.45) | <0.001 |
| −0.02 (−0.03 – −0.01)‡ | <0.001 | ||
| Area FL (cm2) | 5.0 (3.7 – 6.4) | 0.30 (−0.12 – 0.73) | 0.159 |
| Area FLT (cm2) | 2.1 (0.0 – 3.6) | 0.89 (0.41 – 1.38) | <0.001 |
| Total Area (cm2) | 8.0 (6.6 – 10.1) | 1.61 (0.98 – 2.25) | <0.001 |
| Grading FLT††† | 1.0 (0.0 – 1.0) | ||
| Number of ICA from TL (n) | 7.0 (3.5 – 9.0) | −0.08 (−0.21 – 0.05) | 0.222 |
| Number of ICA from FL (n) | 8.0 (5.0 – 11.5) | −0.19 (−0.36 – −0.02) | 0.033 |
| Total numbers of ICA (n) | 16.0 (13.0 – 18.0) | −0.57 (−0.81 – −0.32) | <0.001 |
| 0.04 (0.02 – 0.07)‡ | 0.002 |
Baseline values are given in median and interquartile range. Coefficients of time refer to the average linear (or quadratic) increase or decrease of each morphologic parameter per year. Max: Maximum; mm: millimeter; TL: true lumen, FL: false lumen; FLT: false lumen thrombosis; ICA: intercostal arteries
†
Computed using all follow-up measurements available, using mixed-effects regression. Estimates are accompanied by 95% confidence intervals.
‡
Results of time-squared to accommodate non-linear change over time.
†††
Coefficient of time could not be modeled due to the distribution.