. Author manuscript; available in PMC: 2023 Oct 5.

Published in final edited form as: J Thorac Cardiovasc Surg. 2019 Oct 31;161(4):1184–1190.e2. doi: 10.1016/j.jtcvs.2019.10.074

Table 3:

Associations between changes in morphological features over time and the occurrence of late adverse events

	Univariable HR (95% CI)	P-value	Multivariable^‡ HR (95% CI)	P-value
Max. major aortic diameter (mm)	1.21 (1.13 – 1.30)	< 0.001	1.25 (1.13 – 1.37)	<0.001
Max. minor aortic diameter (mm)	1.16 (1.10 – 1.23)	< 0.001	1.16 (1.08 – 1.24)	<0.001
Size of intima tear axial (mm)	1.03 (0.99 – 1.03)	0.145	NA
Size of intima tear sagittal (mm)	1.04 (0.98 – 1.10)	0.171	NA
Circumferential extent of TL (°)	0.96 (0.94 – 0.98)	< 0.001	0.96 (0.94 – 0.98)	< 0.001
Circumferential extent of FL (°)	1.03 (1.01 – 1.05)	0.004	1.04 (1.01 – 1.06)	0.004
Area TL (cm²)	0.97 (0.68 – 1.38)	0.874	NA
Area FL (cm²)	1.13 (1.02 – 1.25)	0.017	1.06 (0.94 – 1.20)	0.326
Area FLT (cm²)	1.30 (1.16 – 1.46)	< 0.001	1.53 (1.25 – 1.88)	<0.001
Total Area (cm²)	1.18 (1.10 – 1.27)	<0.001	1.26 (1.14 – 1.39)	<0.001
Number of ICA from TL (n)	0.93 (0.80 – 1.08)	0.330	NA
Number of ICA from FL (n)	1.09 (0.95 – 1.25)	0.235	NA
Total numbers of ICA (n)	1.06 (0.92 – 1.23)	0.407	NA

^‡

Association between morphological feature change over time and time-to-occurrence of a LAE corrected for the baseline values of all other features significant in the univariable analysis, and corrected for the presence of connective tissue disease. HR: hazard ratio; CI: confidence interval; Max: maximum; mm: millimeter; TL: true lumen; FL: false lumen; FLT: false lumen thrombosis; ICA: intercostal arteries; NA: not applicable (not significant in univariable analysis).