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. 2023 Aug 28;12(10):689–706. doi: 10.1093/stcltm/szad050

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© The Author(s) 2023. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.

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Figure 6. — The role of MSC-CM treatment in mRNA and protein expressions of high glucose-induced HUVECs and HSFs. (A) mRNA expressions of inflammation (TNF-α, IL-1β, and IL-6), tube formation (ET-1), and senescence (p16) related genes in HUVECs. (B) mRNA expressions of collagen synthesis (COL1, COL3, and COL4), oxidative stress (SOD1 and SOD2) related genes in HSFs. (C) Representative protein expression images of PCNA (HUVECs and HSFs). (D) Relative protein levels of PCNA/β-actin (HUVECs and HSFs). Data was presented as mean ± SD, *P < .05 and **P < .01 vs control level, ^#P < .05 and ^##P < .01 vs model level.