Table 5.
Demographic characteristics and anatomical follow-up parameters of Group 3 (management with WJ-MSC + rEMS combination).
| Patient no | Genetic mutation | Eye | Horizontal EZW | Vertical EZW | FAF field | |||
|---|---|---|---|---|---|---|---|---|
| Time0 | Time1 | Time0 | Time1 | Time0 | Time1 | |||
| 1 | RHO | R | 2.49 | 2.51 | 1.98 | 2.04 | 5.2 | 5.3 |
| L | 2.61 | 2.63 | 2.20 | 2.24 | 5.7 | 5.8 | ||
| 2 | USH2A | R | 6.18 | 6.21 | 5.72 | 5.74 | 34.2 | 35,7 |
| L | 6.14 | 6.16 | 5.68 | 5.71 | 34.9 | 36,2 | ||
| 3 | RPGR | R | 1.21 | 0.85 | 1.34 | 0.94 | 1.6 | 1.3 |
| L | 1.31 | 0.92 | 1.39 | 0.97 | 1.8 | 1.3 | ||
| 4 | C2ORF | R | 4.72 | 4.68 | 4.61 | 4.57 | 21.6 | 20.5 |
| L | 4.63 | 4.57 | 4.58 | 4.52 | 21.2 | 20.3 | ||
| 5 | USH2A | R | 4.02 | 4.02 | 4.06 | 4.05 | 14.9 | 14.8 |
| L | 4.22 | 4.21 | 4.26 | 4.26 | 18.0 | 18.0 | ||
| 6 | PDE6B | R | 3.56 | 3.50 | 3.69 | 3.62 | 14.1 | 13.8 |
| L | 3.63 | 3.55 | 3.74 | 3.68 | 14.6 | 14.2 | ||
| 7 | RP1 | R | 2.05 | 1.97 | 2.03 | 1.96 | 4.7 | 4.5 |
| L | 2.11 | 2.07 | 2.10 | 2.04 | 5.0 | 4.7 | ||
| 8 | USH2A | R | 3.14 | 3.14 | 3.18 | 3.18 | 10.0 | 10.0 |
| L | 3.22 | 3.21 | 3.28 | 3.27 | 10.5 | 10.5 | ||
| 9 | PDE6A | R | 3.29 | 3.21 | 3.22 | 3.17 | 10.6 | 10.3 |
| L | 3.17 | 3.10 | 3.28 | 3.21 | 10.4 | 10.1 | ||
| 10 | USH2A | R | 2.98 | 2.98 | 3.00 | 3.00 | 9.1 | 9.1 |
| L | 3.11 | 3.11 | 3.08 | 3.08 | 9.6 | 9.6 | ||
| 11 | BBS6 | R | 2.01 | 2.00 | 2.11 | 2.10 | 4.2 | 4.2 |
| L | 2.10 | 2.08 | 2.06 | 2.05 | 4.4 | 4.3 | ||
| 12 | RHO | R | 3.56 | 3.58 | 3.54 | 2.56 | 13.0 | 13.1 |
| L | 3.68 | 3.69 | 3.66 | 3.67 | 13.6 | 13.7 | ||
| 13 | RHO | R | 4.71 | 4.71 | 4.68 | 4.68 | 23.6 | 23.6 |
| L | 4.89 | 4.90 | 4.59 | 4.59 | 24.1 | 24.1 | ||
| 14 | USH2A | R | 2.97 | 2.97 | 2.91 | 2.91 | 9.8 | 9.8 |
| L | 2.91 | 2.90 | 2.83 | 2.83 | 9.2 | 9.2 | ||
| 15 | EYS | R | 1.56 | 1.52 | 1.59 | 1.55 | 2.5 | 2.3 |
| L | 1.63 | 1.58 | 1.58 | 1.53 | 2.7 | 2.5 | ||
| 16 | RHO | R | 5.10 | 5.09 | 5.05 | 5.03 | 30.6 | 30.5 |
| L | 5.21 | 5.19 | 5.11 | 5.09 | 31.9 | 31.7 | ||
Time0 (baseline): just before the WJ-MSC and Magnovision application.
Time1: 36th month after injection and 36th month of weekly rEMS sessions.
EZW, ellipsoid zone width (mm); FAF, fundus autofluorescence (mm2); rEMS, repetitive electromagnetic stimulation; WJ-MSCs, Wharton’s jelly derived mesenchymal stem cells.