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YAP interacts with OGT for O-GlcNAcylation. (A) Heatmap illustrating proteins in the Con-sh and OGT-sh groups of HEC-1-B cells that were O-GlcNAcylated. (B) YAP O-GlcNAcylation was detected using a co-immunoprecipitation assay after changing the global O-GlcNAcylation level. (C and D) Co-immunoprecipitation assays demonstrated the interaction between OGT and YAP in AN3CA and HEC-1-B cells. YAP, Yes-associated protein; OGT, O-GlcNAc transferase.
