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. 2023 Jul 10;63(2):98. doi: 10.3892/ijo.2023.5546

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Copyright: © Zheng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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circRPS19 promotes GC cell proliferation and aerobic glycolysis in vivo. (A) Tumor volume was recorded every 3 days. (B) Representative image and (C) weight of excised tumors. (D) Immunohistochemistry was implemented to investigate the expression of Ki-67, HK2 and USP7 in tumor tissues. (E) Glucose consumption and (F) lactate production were examined in tumor tissues. ^**P<0.01 compared with control group. circRPS19, circRNA ribosomal protein S19; GC, gastric cancer; HK2, hexokinase 2; USP7, ubiquitin-specific processing protease 7; si, small interfering; NC, negative control.