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. 2023 Aug 17;37(13):1959–1969. doi: 10.1097/QAD.0000000000003689

Fig. 4.

The effect of single nucleotide polymorphism rs4131564 on viral replication and antibody neutralization.

Fig. 4

(a) HIV-1 replication of NL4.3 or NL4.3-BaL, as measured by p24 production, in donor PBMC with or without SNP rs4131564. (B) IC50 (ug/ml) of VRC01 and 2G12 neutralization of NL4.3-BaL produced in PBMC from donors carrying the minor or major allele of rs4131564. Each virus was tested in triplicate and the mean and SD are shown. PBMC, peripheral blood mononuclear cells; SNP, single nucleotide polymorphism.