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. 2023 Oct 3;64(13):4. doi: 10.1167/iovs.64.13.4

Figure 1.

Figure 1.

Three general conditions that must be met for MR analysis. Assumption 1: This assumption reflects the causal link between IVs and the exposure of interest. Assumption 2: This assumption represents the causal connection between IVs and potential confounding factors that influence both the exposure and the outcome. Assumption 3: This assumption signifies the causal relationship between IVs and the outcome being studied.