Forest plots of the multivariable analysis. Forest plot of subgroup analyses showing the HR for death and 95% CI in (A) the multivariable analysis of the donor versus no donor comparison and (B) the multivariable time-dependent analysis where HCT was considered as a time-dependent variable. Multivariable Cox regression analysis was used, with adjustment for treatment arm (A) or HCT (B), TP53 allelic state, DDX41 mutation, KMT2APTD, complex karyotype, duration of disease, IPSS score, sex, age, and performance score. ECOG, Eastern Cooperative Oncology Group; HCT, hematopoietic cell transplantation; HR, hazard ratio; IPSS, International Prognostic Scoring System; MDS, myelodysplastic syndrome; OS, overall survival.