Table 3.
Univariate logistic regression analysis of the training cohort.
| Variable | All-cause early death | Cancer-specific early death | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Age | ||||||
| <40 | 1.1 | 0.69–1.75 | .701 | 1.08 | 0.67–1.73 | .757 |
| 40–65 | 1.7 | 1.07–2.72 | .026 | 1.55 | 0.97–2.49 | .067 |
| >65 | 1 (ref) | 1 (ref) | ||||
| Sex | ||||||
| Male | 1 (ref) | 1 (ref) | ||||
| Female | 0.95 | 0.76–1.2 | .69 | 0.97 | 0.77–1.22 | .77 |
| Race | ||||||
| White | 1 (ref) | 1 (ref) | ||||
| Black | 1.08 | 0.46–2.54 | .86 | 1.2 | 0.51–2.82 | .679 |
| Other | 0.75 | 0.37–1.5 | .416 | 0.73 | 0.36–1.49 | .391 |
| Marital | ||||||
| Married | 1 (ref) | 1 (ref) | ||||
| Unmarried | 1.4 | 1.14–1.72 | .002 | 1.35 | 1.09–1.66 | .006 |
| Primary site | ||||||
| Skin, NOS | 1 (ref) | 1 (ref) | ||||
| Skin other/unspecific parts of face | 0.54 | 0.25–1.16 | .115 | 0.52 | 0.24–1.14 | .103 |
| Skin of scalp and neck | 0.27 | 0.15–0.46 | <.001 | 0.3 | 0.17–0.52 | <.001 |
| Skin of trunk | 0.64 | 0.46–0.89 | .009 | 0.6 | 0.43–0.85 | .003 |
| Skin of upper limb and shoulder | 0.59 | 0.36–0.95 | .029 | 0.59 | 0.36–0.95 | .031 |
| Skin of lower limb and hip | 0.31 | 0.19–0.52 | <.001 | 0.35 | 0.21–0.58 | <.001 |
| Choroid | 0.08 | 0.01–0.61 | .014 | 0.09 | 0.01–0.68 | .019 |
| External ear | 0.27 | 0.06–1.24 | .091 | 0.3 | 0.06–1.38 | .121 |
| Other rare sites | 0.33 | 0.14–0.78 | .011 | 0.37 | 0.16–0.87 | .023 |
| Melanoma type | ||||||
| Malignant melanoma, NOS | 1 (ref) | 1 (ref) | ||||
| Nodular melanoma | 0.46 | 0.3–0.7 | <.001 | 0.51 | 0.34–0.78 | .002 |
| Superficial spreading melanoma | 0.45 | 0.19–1.06 | .066 | 0.41 | 0.17–1.02 | .054 |
| Spindle cell melanoma, NOS | 0.47 | 0.17–1.3 | .145 | 0.52 | 0.19–1.45 | .214 |
| Amelanotic melanoma | 1.08 | 0.47–2.49 | .853 | 1.01 | 0.43–2.36 | .978 |
| Other rare types | 0.31 | 0.14–0.68 | .003 | 0.35 | 0.16–0.76 | .008 |
| T Stage | ||||||
| T0 | 1 (ref) | 1 (ref) | ||||
| T1–T2 | 0.34 | 0.22–0.55 | <.001 | 0.36 | 0.22–0.57 | <.001 |
| T3–T4 | 0.51 | 0.38–0.7 | <.001 | 0.52 | 0.38–0.71 | <.001 |
| TX | 1.13 | 0.89–1.44 | .319 | 1.06 | 0.83–1.35 | .654 |
| N Stage | ||||||
| N0 | 1 (ref) | 1 (ref) | ||||
| N1 | 1.06 | 0.78–1.43 | .718 | 1.09 | 0.8–1.47 | .58 |
| N2 | 0.27 | 0.13–0.58 | .001 | 0.3 | 0.14–0.64 | .002 |
| N3 | 0.68 | 0.42–1.09 | .108 | 0.6 | 0.37–0.99 | .045 |
| NX | 1.94 | 1.51–2.48 | <.001 | 1.87 | 1.45–2.39 | <.001 |
| Surgery | ||||||
| No | 1 (ref) | 1 (ref) | ||||
| Yes | 0.34 | 0.26–0.44 | <.001 | 0.36 | 0.28–0.48 | <.001 |
| Radiation | ||||||
| No | 1 (ref) | 1 (ref) | ||||
| Yes | 0.82 | 0.66–1.01 | .063 | 0.88 | 0.71–1.09 | .257 |
| Chemotherapy | ||||||
| No | 1 (ref) | 1 (ref) | ||||
| Yes | 0.32 | 0.25–0.41 | <.001 | 0.35 | 0.27–0.45 | <.001 |
| Bone metastasis | ||||||
| No | 1 (ref) | 1 (ref) | ||||
| Yes | 1.48 | 1.16–1.87 | .001 | 1.42 | 1.11–1.8 | .005 |
| Brain metastasis | ||||||
| No | 1 (ref) | 1 (ref) | ||||
| Yes | 1.89 | 1.53–2.34 | <.001 | 1.9 | 1.53–2.35 | <.001 |
| Liver metastasis | ||||||
| No | 1 (ref) | 1 (ref) | ||||
| Yes | 1.94 | 1.55–2.42 | <.001 | 1.98 | 1.58–2.48 | <.001 |
| Lung metastasis | ||||||
| No | 1 (ref) | 1 (ref) | ||||
| Yes | 1.76 | 1.43–2.17 | <.001 | 1.74 | 1.4–2.15 | <.001 |