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. 2023 Oct 6;102(40):e35407. doi: 10.1097/MD.0000000000035407

Table 2.

Incidence rates of events during follow-up per 100 person-yr of patients prescribed raltegravir and other third-line drugs for salvage regimens.

Events during follow-up Eligible population
(n = 168; 178.05 p-y)
Matched subset
(n = 90; 98.06 p-y)
IRR (95%CI)*; P
Raltegravir
(n = 123, 129.54 p-y)
Other drugs
(n = 45, 48.51 p-y)
Raltegravir
(n = 45, 49.55 p-y)
Other drugs
(n = 45, 48.51 p-y)
Drug toxicity 0.77 2.06 0.00 2.06 −, .49
Treatment interruption 12.35 0.00 8.07 0.00 −, .06
Virologic failure 2.32 4.12 2.02 4.12 .49 (.04–5.40), .61
Loss of follow-up 3.86 4.12 6.05 4.12 1.47 (.25–8.79), .70
Death 4.63 6.18 4.04 6.18 .65 (.11–3.91), .67

CI = confidence interval, p-y = person-year.

*

IRR (incidence rate ratio) and 95% CI for rates of each event by salvage regimen were calculated by Poisson regression, where other drugs were considered as comparators.

Wald test P value.