TABLE 4.

Clinical isolates of C. albicans susceptible to azole agents, by year

Year	Total no. of isolates	% Isolates susceptible to the following agents:				Fluconazole use (no. of doses/year)
		Fluconazole	Ketoconazole	Miconazole	Itraconazole
1984	17	100	100	100	—a	0
1985	20	100	100	100	—	0
1986	20	100	100	100	—	0
1987	19	100	100	100	—	0
1988	20	100	100	100	—	0
1989b	19	100	100	100	—	0
1990	19	100	89	100	—	Not available
1991	20	100	100	100	—	5,698
1992	16	100	100	100	—	7,809
1993	18	72	89	78	—	7,832
1994	50 (36)c	86 (89)	82 (78)	78 (83)	—	10,117
1995	65 (37)	77 (89)	92 (92)	73 (84)	—	6,728
1996	54 (36)	89 (94)	94 (97)	94 (97)	80 (83)	7,971
1997	42 (34)	90 (91)	100	95 (97)	88 (88)	9,438

^a—, routine itraconazole testing was performed with fresh clinical isolates obtained in 1996 and 1997. 

^bYear that fluconazole was added to the hospital formulary. 

^cData in parentheses are data for isolates from sterile body sites from 1994 through 1997.