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. 2023 Oct 5;18(10):e0287766. doi: 10.1371/journal.pone.0287766

Table 1. Attributes and levels in module 1.

Effect category Attribute Levels
Treatment type Route of administration
  • Oral

  • Injection

  • Intravenous

Benefits Chance of complete response
  • 50 out of 100 (50%)

  • 20 out of 100 (20%)

  • 0 out of 100 (0%)

Progression-free survival (time until cancer gets worse)
  • 30 months

  • 18 months

  • 12 months

Toxicities Gastrointestinal problems
  • No stomach problems

  • Severe diarrhea

  • Severe nausea

Neurotoxicity No problems with the nervous system
  • Peripheral neuropathy

  • CNS neurotoxicity

Insomnia
  • No insomnia

  • Mild insomnia

  • Severe insomnia

Adverse-event risks Chance of cytokine release syndrome (CRS)
  • 0 out of 100 (0%)

  • 3 out of 100 (3%)

  • 5 out of 100 (5%) or

    10 out of 100 (10%)

CNS = Central nervous system.