TABLE 2.
Sensitivities of the yor1 gene mutants
| Compound (MIC units) | MICa
|
||||
|---|---|---|---|---|---|
| DKD-5D (wild type) | SH3328 (wild type) | AL22-4A (aur3R) | A141-9A (yor1::URA3) | A07 (pWL7) | |
| AbA (μg/ml) | 0.4 | 0.4 | >25 | 0.2 | 5.0 |
| Cycloheximide (μg/ml) | 0.2 | 0.4 | 0.2 | 0.2 | 0.2 |
| Miconazole (μg/ml) | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
| Amphotericin B (μg/ml) | 12.5 | 6.3 | 6.3 | 6.3 | 3.2 |
| CdCl2 (μg/ml) | 50 | 50 | 50 | 50 | 50 |
| LiCl (μg/ml) | 8.4 | 4.2 | 8.4 | 4.2 | 4.2 |
| CaCl2 (mg/ml) | 55.5 | 11.1 | 11.1 | 27.8 | 27.8 |
| NaCl (mg/ml) | 87.6 | 87.6 | 87.6 | 87.6 | 87.6 |
a
MICs were determined on YPD (pH 6.4) agar plates containing each compound. The plates were incubated at 30°C for 2 days.