Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Oct 5;18(10):e0290034. doi: 10.1371/journal.pone.0290034

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 Nishiyama et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Fig 4 — (A) and (B) Estimation of leukocyte fraction in H. pylori-infected stomach (A) and DSS-treated colon (B). The fraction of infiltrating leukocytes was 7.8% in H. pylori-infected stomach (HP 2) and 4.3% in DSS-treated colon (DSS 1), but 1.3% and 0.1% in their corresponding control samples (ctrl 3 and ctrl 2). (C) Histological estimation of a leukocyte fraction. The fraction of infiltrating leukocytes was histologically estimated by immunofluorescence of a leukocyte marker, Cd45, and DAPI staining. The number of DAPI-stained spots within Cd45-stained regions was counted as that of nuclei of leukocytes. White arrowheads show leukocytes. (D) and (E) The fraction of infiltrating leukocytes in H. pylori-infected stomach estimated using the algorithm with DNA methylation and that obtained histologically. The fraction in infected stomach was 7.6±3.6% and 7.8±1.6% using methylation markers and immunofluorescence, respectively (D). The fraction estimated using two methods was well correlated [R = 0.811 (p = 0.004)] (E).