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. 2023 Sep 25;19(9):e1010973. doi: 10.1371/journal.pgen.1010973

Fig 2. TDP-43 overexpression leads to age-dependent loss of each glial cell type.

Fig 2

Representative confocal images (Scale bar = 10μm.) of equivalent anterior section of the Drosophila brain on days 2,5, and 10 post eclosion for flies control (top) vs flies that express TDP-43 in PNGts (A), SPGts (C), CG (E) ALG (G), EG (I). Quantification of the number of each glial cell type in an equivalent anterior section was determined by counting nuclei labeled by Unc84-2X-GFP, which was co-expressed (B,D,F,H,J). Mean and SD are shown. Students T-test used to compare genotypes within each timepoint. * p<0.05, ***p<0.001. Gal4 lines and full genotypes used for each cell type are listed in methods.