TABLE 2.
Inhibition of viral growth in MDCK cells by BCX-140 determined by the MTT assay
| Virus | IC50 (μM)a |
|---|---|
| A/PR/8/34 (H1N1) | No inhibition up to 500 μM |
| A1/FM/1/47 (H1N1) | 181 ± 50 |
| A/New Jersey/8/76 (H1N1) | No inhibition up to 500 μM |
| A/Singapore/1/57 (H2N2) | 29 ± 5b |
| CA/Aichi/68HAPR8/34NA(H3N2) | 261 ± 133b |
| A/Turkey/Mass/76HA/Beijing/32/92NA[R] (H6N2) | 59 ± 25 |
| B/Allen/45 | 109 ± 93c |
a
Values are means ± standard errors of the means for three determinations except where indicated.
b
Values are means ± standard errors of the means for five determinations.
c
Values are means ± standard errors of the means for four determinations.