TABLE 4.
Elution from RBCsa
| Virus strain (amino acid change) | Elution time (h) from the following:
|
|||
|---|---|---|---|---|
| Chicken RBCs
|
Human RBCs
|
|||
| BCX-140 − | BCX-140 + | BCX-140 − | BCX-140 + | |
| C6A | >18 | >18 | >18 | >18 |
| BCX-140RM2 (Ala-133 to Thr) | 2–3 | Partial | >18 | >18 |
| BCX-140R (Arg-132 to Gln) | 1 | 1 | 1 | >18 |
a
Virus strains C6A, BCX-140RM2, and BCX-140R (8 hemagglutination units) were allowed to agglutinate either chicken or human RBCs at 4°C, and then the elution times observed on warming to 37°C in the presence (+) or absence (−) of BCX-140 were determined.